Certain brain tumors in small children contain cells that develop very similarly to normal brain cells and others that have already developed malignantly, depending on where they are located within the tumor.

More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers from the Medical Faculty at the University of Freiburg has developed an active substance that might in future represent a new treatment option.

University of Tübingen neuroscientists discover new functions of head-direction cells suggesting they may contribute to episodic memory formation.

Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart’s ability to pump blood in the long term. In a current study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis.

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the Weizmann Institute in Israel and at the German Cancer Research Center (DKFZ) have now shown that p53-mutated mouse breast cancer cells reprogram fat cells.

ProGrün project - 30/12/2023

Using proteins extracted from grassland cuttings to produce animal feed and exploit by-product streams

Animal feed often contains protein from soy and importing it causes major environmental harm. In the ProGrün project, researchers at the University of Hohenheim, including a work group led by Prof. Dr. Andrea Kruse, are developing a scalable technological process to extract proteins from grassland cuttings and use them to make sustainable animal feed produced in the region where it will be used.

Alternative construction materials: mycelium-based materials - 20/12/2023

Using fungi to create sustainable and economical mycelium-based materials

Most of us see fungi as just food - and possibly pathogens. This is a mistake, because these amazing organisms are capable of much more: they grow on plant residues of all kinds, forming a dense and interconnected structure as they spread. The resulting material can be moulded into desired shapes and be turned into new sustainable and economically attractive products such as leather and polystyrene substitutes or building materials.

Facade greening with precipitation retention - 19/12/2023

Rain-retaining living walls improve the urban climate and protect against flooding

Due to dense urbanisation and associated soil sealing, heat and heavy rainfall are becoming an increasing problem for people living in cities. Researchers at the German Institutes of Textile and Fibre Research (DITF) in Denkendorf have developed innovative living walls that not only help cool the environment, but also provide flood protection thanks to their water retention properties.

For the first time, the active substance epifadin has been isolated at the University of Tübingen – Epifadin is produced by specific bacteria in the nose and on the skin of humans, has an antibiotic effect, and is the first example of a previously unknown antimicrobial compound class.

Sustainable binder alternative - 18/12/2023

Copied from insects: new biological wood binder under development

Plastic is all around us; and unfortunately, it is not going away any time soon. The search for more sustainable solutions is fully underway. However, binders that degrade only with difficulty or not at all are still used to bond natural materials such as wood and straw - not yet truly environmentally friendly. Fraunhofer researchers are working on an insect-inspired wood binder that makes bonded wood products both resistant and biodegradable.

All-enzyme hydrogels in action - 13/12/2023

Biocatalytic foams enable the sustainable synthesis of complex molecules

Conventional chemical synthesis processes consume large amounts of energy and environmentally harmful solvents. Prof. Dr. Christof Niemeyer’s team at the Karlsruhe Institute of Technology has generated porous, solid foams from crosslinked enzymes that allow the production of high-quality compounds under significantly more environmentally friendly conditions. The novel biocatalysts are also extremely resistant and have a long shelf life.

The German Cancer Society has certified the Center for Personalized Medicine (ZPM) at Heidelberg University Hospital. At the ZPM Heidelberg, patients with advanced and rare cancers and, in future, people with severe chronic inflammatory diseases will receive a molecular genetic analysis. The detailed information can open up new treatment options for those affected.

Professor Dr. Rohini Kuner from the Medical Faculty of Heidelberg University receives the Leibniz Prize of the German Research Foundation (DFG).

urban BioEconomyLab - 07/12/2023

The city as a living laboratory for a bioeconomic, sustainable economic area

Baden-Württemberg is leading the way in the transition to a climate-neutral and sustainable economy. One of the projects undertaken is the Fraunhofer IGB’s "urban BioEconomyLab" project which aims to develop a transformation model and living laboratory to find bioeconomic solutions for the sustainable design of cities and municipal industry. What is new is that the IGB takes a systemic approach, focusing on biobased and circular value…

Computer-assisted genome mining - 04/12/2023

Natural product genomics opens up new avenues in the search for antibiotics

Antibiotic-resistant pathogens are increasingly endangering our health. Since most of the drugs currently in use are based on secondary metabolites produced by bacteria or fungi, the research group of Prof. Dr. Nadine Ziemert in Tübingen is developing bioinformatic tools to specifically search the genome of these organisms for previously unknown antimicrobial agents.

University of Tübingen researchers reverse the evolution of a class of antibiotics to gain insights for the development of new drugs.

Heidelberg scientists unveil genetic programmes controlling the development of cellular diversity in the cerebellum of humans and other mammals. The research results have now been published in the journal Nature.

The progression of multiple sclerosis (MS) can usually be slowed down with medication, but a cure is currently not possible. It is now established that Epstein-Barr viruses are involved in the development of MS. However, it is not known how the pathogens trigger the disease. The European Union is now funding the international research consortium BEHIND-MS as part of its HORIZON Europe program.

Recent research shows effectiveness of biosurfactants - 28/11/2023

Combating oil spills - biosurfactants can stimulate microbial oil degradation

Oil spills from drilling platforms and tankers cause environmental pollution and a loss of biodiversity. Researchers at the University of Stuttgart, among others, are now using biosurfactants to improve the management of oil spills: their latest research shows that biosurfactants lead to better microbiological degradation of oil components in seawater compared to conventional dispersants.

The AlbLavendel project - 20/11/2023

Swabian lavender cultivation: aesthetic and sustainable

Blue-violet, fragrant fields like those in Provence may soon become a common sight in the Swabian Alb. As part of the AlbLavendel project, the University of Hohenheim along with the company naturamus GmbH and the German Institutes of Textile and Fibre Research Denkendorf has started to investigate the cultivation of lavender, the production of essential oils and the use of distillation residues for producing textile fibres in the local region.

Pancreatic cancer is one of the deadliest types of cancers in humans. Chemotherapies attack not only the tumor cells but also healthy cells throughout the body. Innovative nanoparticles could be a new approach to treat cancer more precisely. The approach was developed by a research team from the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the Karlsruhe Institute of Technology.