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DNA nanotechnology - 25/08/2023
The physicists Prof. Dr. Kerstin Göpfrich and Prof. Dr. Laura Na Liu want to understand life from the bottom up. They intend to do this by constructing an artificial cell. However, rather than natural protein building blocks, they are using 3D-DNA structures as construction material. The first step involved creating an artificial cell skeleton that dynamically assembles and disassembles like the biological model and can transport vesicles.
https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-cytoskeleton-made-dna-synthetic-cells
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Project BlindZero - 03/08/2023
Thousands of cornea transplants are performed every year. However, donors are rare and the procedure is not always without complications. Researchers at the University of Heidelberg are developing an innovative technique in the project BlindZero. It involves ‘printing’ human corneas directly onto patients’ eyes using 3D bioprinting. The reprogrammed genetically engineered cells used for this purpose are not expected to cause a rejection reaction.
https://www.gesundheitsindustrie-bw.de/en/article/news/hope-patients-eye-diseases-human-cornea-3d-printers
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NeuroQ project - 26/07/2023
Could people suddenly be able to move again decades after being paralysed? State-of-the-art quantum sensors integrated in exoskeletons could make this possible. Technology being developed as part of the BMBF-funded NeuroQ beacon project by researchers from organisations including the Fraunhofer IAF, the Charité in Berlin and the University of Stuttgart might achieve even more: besides facilitating movement, it could also help cure paralysis.
https://www.gesundheitsindustrie-bw.de/en/article/news/quantum-sensors-exoskeletons-can-quantum-physics-beat-paralysis
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Press release - 13/07/2023
Wearable medical devices, such as soft exoskeletons that provide support for stroke patients or controlled drug delivery patches, have to be made of materials that can adapt intelligently and autonomously to the wearer's movements and to changing environmental conditions. These are the type of autonomously switchable polymer materials that have recently been developed by researchers at the University of Stuttgart and the University of…
https://www.gesundheitsindustrie-bw.de/en/article/press-release/intelligent-rubber-materials
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Predicting the success of cancer treatment - 20/06/2023
Cancer immunotherapies use the body's own defences to fight tumour cells. An international consortium of researchers from Germany and the USA led by the DKFZ in Heidelberg has demonstrated that the effectiveness of CAR T-cell therapies greatly depends on the composition of the gut microbiome. The researchers have also developed a model for predicting the long-term response to the treatment.
https://www.gesundheitsindustrie-bw.de/en/article/news/focusing-gut-microbiome-car-t-cell-therapy
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Press release - 20/06/2023
Scientists at the Max Planck Institute for Intelligent Systems in Stuttgart have developed a magnetically controlled soft medical robot with a unique, flexible structure inspired by the body of a pangolin. The robot is freely movable despite built-in hard metal components. Thus, depending on the magnetic field, it can adapt its shape to be able to move and can emit heat when needed.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/pangolin-inspiration-medical-robot
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Innovative materials - 14/06/2023
Conserving wood by producing furniture and other objects from wood-based materials with the help of microorganisms? That is exactly what a team of researchers from the University of Freiburg and the Leibniz Institute for New Materials (INM) in Saarbrücken is working on in the DELIVER project. The aim is to create a database of materials with a broad range of controllable properties for various applications that can be produced from wood waste.
https://www.biooekonomie-bw.de/en/articles/news/reinventing-wood-programmable-bacteria
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Press release - 05/06/2023
Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney. The scientists from the Institute of Genetic Epidemiology at the Medical Center - University of Freiburg measured tiny molecules, so-called metabolites, which occur in blood and urine and reflect our metabolism, in samples from more than 5,000 study participants.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-findings-about-human-metabolic-processes
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Reduced immunosuppression possible in transplantations - 05/06/2023
Traditionally, transplant recipients have had to take immunosuppressive medication for life to prevent organ rejection. However, there are considerable side effects involved. Using modified immune cells (MICs), TolerogenixX GmbH from Heidelberg has now managed to generate donor-specific tolerance in recipients of living kidney transplants without suppressing the overall immune system.
https://www.gesundheitsindustrie-bw.de/en/article/news/modified-immune-cells-produce-donor-specific-tolerance
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Detecting drug resistance of tumour cells - 25/05/2023
Lung cancer is one of the most common cancers and has a particularly high mortality rate. A significant challenge in treating this disease lies in the resistance of lung tumours to conventional drug therapies, rendering chemotherapy ineffective. There is hope on the horizon as a team of experts from Baden-Württemberg has joined forces to develop an innovative AI-supported test procedure that paves the way for individualised therapy approaches.
https://www.gesundheitsindustrie-bw.de/en/article/news/ai-assisted-diagnostics-declares-war-lung-cancer
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Press release - 22/05/2023
Volkswagen Foundation to fund international research project with around 1.5 million euros. Interdisciplinary team led by the Institute for Global Health at Heidelberg University Hospital to research the transmission of pathogens from animals to humans in Thailand and Laos. Long-term goal is to develop sustainable preventive measures against future pandemics.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/prevention-pandemics
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Press release - 17/05/2023
Centromeres, the DNA sections often found at the center of the chromosomes, display enormous interspecies diversity, despite having the same vital role during cell division across almost the entire tree of life. An international team of researchers has discovered that the variation in centromere DNA regions can be strikingly large even within a single species. The findings, now published in the journal Nature, shed light on the molecular…
https://www.gesundheitsindustrie-bw.de/en/article/press-release/playing-hide-and-seek-centromere
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3D-Thermocell project - 17/05/2023
Replacing plastic – for example in packaging – is not that easy but nevertheless urgently needed. In the 3D-Thermocell project, researchers at DHBW Karlsruhe are currently developing new plastic substitute products made of thermoformable paper as a renewable resource, which should be cheap and light and easy to dispose of along with waste paper. The characterisation and application of demonstration models will start soon.
https://www.biooekonomie-bw.de/en/articles/paper-instead-plastic-sustainable-packaging-good-conscience
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Press release - 16/05/2023
This year's Venice Architecture Biennale sees itself as a "Laboratory of the Future". Bio-composites are not just dreams of the future in architecture. The German Institutes of Textile and Fiber Research (DITF) have developed a sustainable material for support profiles and connecting nodes, which will be on display at Palazzo Mora during the Biennale from May 20 to November 26.
https://www.biooekonomie-bw.de/en/articles/pm/bioverbundwerkstoff-auf-der-architektur-biennale-venedig
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Press release - 09/05/2023
Proteins have characteristic amino acid sequences, the analysis of which is fundamental for research and medicine. These can be decoded; however, so-called protein sequencing is expensive and time-consuming. A large-scale research project led by Prof. Dr. Jan Behrends from the Institute of Physiology at the University of Freiburg now aims to establish a new technology for protein sequencing using nanopores, which will be rapid and cost-effective.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-strategy-clinically-relevant-protein-sequencing
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Diatoms as a biorefinery - 05/05/2023
Renewable raw materials that can be used as alternatives to fossil resources already exist. However, to turn them into everyday products, plant oils and other renewable raw materials not only have to be extracted, but often have to undergo complex chemical processing. Researchers at the University of Konstanz have now converted microalgae cells into tiny refineries to produce and upgrade raw materials, creating a supply of sustainable chemicals.
https://www.biooekonomie-bw.de/en/articles/news/microalgae-sustainable-chemical-production-mini-factory
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Press release - 04/05/2023
Triple-negative breast cancer (TNBC) is the most aggressive and deadly form of breast cancer with limited treatment options. Tumor growth and relapse of TNBC are driven by breast cancer stem cells, and improved therapies that can eliminate those hardy cells are urgently needed. Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for…
https://www.gesundheitsindustrie-bw.de/en/article/press-release/gamma-delta-t-cells-can-fight-aggressive-breast-cancer
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Press release - 26/04/2023
Ready-made meals are ideal for quickly satisfying hunger. However, the quick snacks produce a lot of environmentally harmful plastic waste. To tackle this problem, the student team EDGGY from the University of Hohenheim in Stuttgart rolled up its sleeves and developed edible packaging made from eggshells and other plant-based raw materials. And even better: they simply dissolve in the hot water and can be eaten as an additional protein boost.
https://www.biooekonomie-bw.de/en/articles/pm/Simply-EGG-genious-Students-invent-edible-packaging-from-eggshells
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Press release - 25/04/2023
Roboticists at the Max Planck Institute for Intelligent Systems in Stuttgart have developed a jellyfish-inspired underwater robot with which they hope one day to collect waste from the bottom of the ocean. The almost noise-free prototype can trap objects underneath its body without physical contact, thereby enabling safe interactions in delicate environments such as coral reefs. Jellyfish-Bot could become a tool for environmental remediation.
https://www.biooekonomie-bw.de/en/articles/pm/jellyfish-robots-could-one-day-clean-worlds-oceans
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"Programmable" polymer materials - 24/04/2023
It is impossible to imagine medicine without 3D printing, which can be used to make implants or for culturing cells and tissues. It is now possible for 3D objects to be given an added dimension, namely an ability to make simple autonomous movements, by changing their size. Researchers at Heidelberg University have been able to produce microscopically small 4D structures from intelligent polymers that can be tailored to individual requirements.
https://www.gesundheitsindustrie-bw.de/en/article/news/medicine-future-intelligent-4d-polymers-printer
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Press release - 21/04/2023
In collaboration with the project partners CG TEC, Cordenka, ElringKlinger, Fiber Engineering and Technikum Laubholz, the DITF are developing a new fiber composite material (CELLUN) with reinforcing fibers made of cellulose. The matrix of the material is a thermoplastic cellulose derivative. CELLUN made from renewable biopolymers enables the replacement of glass or carbon fibers in the production of industrial molded parts.
https://www.biooekonomie-bw.de/en/articles/pm/cellun-fiber-composite-made-biopolymers
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