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Event - - Regensburg, Kongress/Symposiumhttps://www.gesundheitsindustrie-bw.de/en/event/gcsb-2024-german-conference-synthetic-biology-2024 -
Event - - Curious2024 – Future Insight™ Conference
Mainz, Kongress/Symposiumhttps://www.gesundheitsindustrie-bw.de/en/event/curious-2024-future-insight-conference -
Press release - 12/02/2024 AI-supported image analysis: metrics determine quality
How well do the algorithms used in the AI-supported analysis of medical images perform their tasks? This depends to a large extent on the metrics used to evaluate their performance. An international consortium led by scientists from the German Cancer Research Center and the National Center for Tumor Diseases has compiled the knowledge available worldwide on the specific strengths, weaknesses and limitations of the various validation metrics.
https://www.gesundheitsindustrie-bw.de/en/article/news/ai-supported-image-analysis-metrics-determine-quality -
Press release - 07/02/2024 The unexpected long-term consequences of female fertility
The constant remodeling of the organs of the female reproductive tract during the reproductive cycle leads to fibrosis and chronic inflammation over the years. Scientists from the German Cancer Research Center (DKFZ) have now uncovered these unexpected long-term consequences of female reproductive function in mice. The results have been published in the scientific journal CELL.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/die-unerwartete-auswirkung-der-weiblichen-fortpflanzungsfaehigkeit -
Press release - 06/02/2024 New T-FINDER Platform Provides Deep Insights Into T Cell Responses Against Novel Cancer Vaccine
BioMed X and the Universitätsmedizin Mannheim announced today the publication of two manuscripts in the field of cancer immunology in the journal Science Advances. The work is based on a collaboration bet- ween both institutions and researchers at the German Cancer Research Center (DKFZ), the Heidelberg Uni- versity, and the Helmholtz Institute for Translational Oncology (HI-TRON).
https://www.gesundheitsindustrie-bw.de/en/article/press-release/neue-t-finder-plattform-liefert-tiefe-einblicke-t-zell-antwort-auf-neuartigen-krebsimpfstoff -
Press release - 02/02/2024 Epigenetic status determines metastasis
Scientists from the German Cancer Research Center (DKFZ) and Medical Faculty Mannheim of the Heidelberg University investigated in mice how spreading tumor cells behave at the site of metastasis: Some tumor cells immediately start to form metastases. Others leave the blood vessel and may then enter a long period of dormancy. What determines which path the cancer cells take is their epigenetic status.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/epigenetischer-status-entscheidet-ueber-metastasierung -
Press release - 02/02/2024 University of Stuttgart successful with cluster draft proposals
The German Research Foundation (DFG) has announced the first pivotal decisions for the "Clusters of Excellence" funding line as part of the Excellence Strategy of the German federal and state governments. The University of Stuttgart has been given the green light for two new cluster initiatives.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/universitaet-stuttgart-mit-clusterskizzen-erfolgreich -
Press release - 31/01/2024 Precursor of Cholesterol Protects Cancer Cells From Cell Death and Makes them Aggressive
A precursor of cholesterol can protect cancer cells from a form of cell death known as ferroptosis. Scientists of the University of Würzburg, the German Cancer Research Center (DKFZ), and the Stem Cell Institute HI-STEM* published this finding in the journal Nature. The results opens up exciting prospects for further improving the treatment of cancer and other diseases associated with oxidative stress and ferroptosis.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/cholesterin-vorstufe-schuetzt-krebszellen-vor-zelltod-und-macht-sie-aggressiver -
Waste recycling in the healthcare sector - 30/01/2024 Sustainability in medical technology: a particular challenge
Quality and safety of medical care are top priorities in the healthcare sector. However, this is often at the expense of climate protection, as not only are energy and raw material consumption very high, but so is the amount of waste generated due to the large number of disposable products. Sustainable product design and improved recycling strategies are therefore required to reduce waste and the CO2 footprint.
https://www.gesundheitsindustrie-bw.de/en/article/news/sustainability-medical-technology-particular-challenge -
Event - 2nd Biointelligence Congress in Stuttgart
Stuttgart (Germany), Kongress/Symposiumhttps://www.gesundheitsindustrie-bw.de/en/event/2nd-biointelligence-congress-stuttgart -
Press release - 18/01/2024 Indicator for liver health status identified
A high-fat, high-sugar diet damages the liver in the long term. Scientists at the German Cancer Research Center (DKFZ) have now identified a characteristic change in the molecular signaling pathways of liver cells in mice that were exposed to such a diet for weeks. It fuels the division activity of hepatocytes and correlates with the risk of patients suffering liver failure after liver surgery.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/indicator-liver-health-status-identified -
Press release - 17/01/2024 Immatics Announces Pricing of $175 Million Public Offering
Immatics N.V. (NASDAQ: IMTX, “Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell-redirecting cancer immunotherapies, announced today the pricing of an underwritten public offering of 15,925,000 ordinary shares at a public offering price of $11.00 per share.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/immatics-announces-pricing-175-dollar-million-public-offering -
Press release - 17/01/2024 AI-based support system for skin cancer diagnostics explains its decisions
Artificial intelligence (AI) can help dermatologists to detect skin cancer. However, many dermatologists distrust the algorithms' decisions, which they cannot comprehend. Scientists at the German Cancer Research Center have now developed an AI-based support system for skin cancer diagnostics that explains its decisions.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/ai-based-support-system-skin-cancer-diagnostics-explains-its-decisions -
Press release - 15/01/2024 Maturation instead of cell death: Defective signalling pathways disrupt immune cell development
Researchers at the Faculty of Medicine of the University of Freiburg discover key factor in the development of immune cells. New approaches for the treatment of ALPS.
https://www.gesundheitsindustrie-bw.de/en/article/maturation-instead-cell-death-defective-signalling-pathways-disrupt-immune-cell-development -
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Health Data Futures project - 11/01/2024 Creating a network of trust
In the three-nation project "Health Data Futures", stakeholders and experts from Germany, France and Switzerland have launched a series of patient-centred innovations. Using various future scenarios, the project partners may be able to come up with even more scenarios.
https://www.gesundheitsindustrie-bw.de/en/article/news/creating-network-trust -
Press release - 10/01/2024 MedTech Company KARL STORZ Acquires British AI Specialist Innersight Labs
The family-owned MedTech company KARL STORZ announces the acquisition of the innovative software manufacturer Innersight Labs Ltd. (ISL) headquartered in London. In addition to state-of-the-art endoscopes, high-end medical devices, and integrated solutions for the operating room, KARL STORZ is also continuing to expand in innovative software solutions.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/medtech-company-karl-storz-acquires-british-ai-specialist-innersight-labs -
Press release - 08/01/2024 Brain tumors in children: Cancer cells become less aggressive as they migrate within the tumor
Certain brain tumors in small children contain cells that develop very similarly to normal brain cells and others that have already developed malignantly, depending on where they are located within the tumor.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/hirntumoren-bei-kindern-krebszellen-werden-auf-ihrer-wanderung-im-tumor-weniger-aggressiv -
Press release - 05/01/2024 Prostate cancer: Newly-developed inhibitor shows massive potential
More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers from the Medical Faculty at the University of Freiburg has developed an active substance that might in future represent a new treatment option.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/prostate-cancer-newly-developed-inhibitor-shows-massive-potential -
Press release - 05/01/2024 How memories are formed in the brain – a new role for the internal compass
University of Tübingen neuroscientists discover new functions of head-direction cells suggesting they may contribute to episodic memory formation.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-memories-are-formed-brain-new-role-internal-compass -
Press release - 04/01/2024 Key player in viral heart inflammation discovered
Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart’s ability to pump blood in the long term. In a current study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/key-player-viral-heart-inflammation-discovered -
Press release - 03/01/2024 Reprogrammed fat cells support tumor growth
Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the Weizmann Institute in Israel and at the German Cancer Research Center (DKFZ) have now shown that p53-mutated mouse breast cancer cells reprogram fat cells.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/reprogrammed-fat-cells-support-tumor-growth -
ProGrün project - 30/12/2023 Using proteins extracted from grassland cuttings to produce animal feed and exploit by-product streams
Animal feed often contains protein from soy and importing it causes major environmental harm. In the ProGrün project, researchers at the University of Hohenheim, including a work group led by Prof. Dr. Andrea Kruse, are developing a scalable technological process to extract proteins from grassland cuttings and use them to make sustainable animal feed produced in the region where it will be used.
https://www.biooekonomie-bw.de/en/articles/news/using-proteins-extracted-grassland-cuttings-produce-animal-feed-and-exploit-product-streams -
Alternative construction materials: mycelium-based materials - 20/12/2023 Using fungi to create sustainable and economical mycelium-based materials
Most of us see fungi as just food - and possibly pathogens. This is a mistake, because these amazing organisms are capable of much more: they grow on plant residues of all kinds, forming a dense and interconnected structure as they spread. The resulting material can be moulded into desired shapes and be turned into new sustainable and economically attractive products such as leather and polystyrene substitutes or building materials.
https://www.biooekonomie-bw.de/en/articles/news/using-fungi-create-sustainable-and-economical-mycelium-based-materials -
Event - - BIO International Convention 2024
San Diego, United States, Kongress/Symposiumhttps://www.gesundheitsindustrie-bw.de/en/event/bio-international-convention-2024 -
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Event - - MedtecLIVE 2024
Stuttgart, Messehttps://www.gesundheitsindustrie-bw.de/en/event/medteclive-2024 -
Facade greening with precipitation retention - 19/12/2023 Rain-retaining living walls improve the urban climate and protect against flooding
Due to dense urbanisation and associated soil sealing, heat and heavy rainfall are becoming an increasing problem for people living in cities. Researchers at the German Institutes of Textile and Fibre Research (DITF) in Denkendorf have developed innovative living walls that not only help cool the environment, but also provide flood protection thanks to their water retention properties.
https://www.biooekonomie-bw.de/en/articles/news/rain-retaining-living-walls-improve-urban-climate-and-protect-against-flooding -
Press release - 18/12/2023 Researchers discover novel antibiotic substance from the human nose
For the first time, the active substance epifadin has been isolated at the University of Tübingen – Epifadin is produced by specific bacteria in the nose and on the skin of humans, has an antibiotic effect, and is the first example of a previously unknown antimicrobial compound class.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-discover-novel-antibiotic-substance-human-nose -
Sustainable binder alternative - 18/12/2023 Copied from insects: new biological wood binder under development
Plastic is all around us; and unfortunately, it is not going away any time soon. The search for more sustainable solutions is fully underway. However, binders that degrade only with difficulty or not at all are still used to bond natural materials such as wood and straw - not yet truly environmentally friendly. Fraunhofer researchers are working on an insect-inspired wood binder that makes bonded wood products both resistant and biodegradable.
https://www.biooekonomie-bw.de/en/articles/news/copied-insects-new-biological-wood-binder-under-development -
All-enzyme hydrogels in action - 13/12/2023 Biocatalytic foams enable the sustainable synthesis of complex molecules
Conventional chemical synthesis processes consume large amounts of energy and environmentally harmful solvents. Prof. Dr. Christof Niemeyer’s team at the Karlsruhe Institute of Technology has generated porous, solid foams from crosslinked enzymes that allow the production of high-quality compounds under significantly more environmentally friendly conditions. The novel biocatalysts are also extremely resistant and have a long shelf life.
https://www.gesundheitsindustrie-bw.de/en/article/news/biocatalytic-foams-enable-sustainable-synthesis-complex-molecules -
Press release - 11/12/2023 Heidelberg center for personalized medicine achieves the highest quality standards
The German Cancer Society has certified the Center for Personalized Medicine (ZPM) at Heidelberg University Hospital. At the ZPM Heidelberg, patients with advanced and rare cancers and, in future, people with severe chronic inflammatory diseases will receive a molecular genetic analysis. The detailed information can open up new treatment options for those affected.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/zentrum-fuer-personalisierte-medizin-heidelberg-erfuellt-hoechste-qualitaetsstandards -
Press release - 08/12/2023 Where does chronic pain come from?
Professor Dr. Rohini Kuner from the Medical Faculty of Heidelberg University receives the Leibniz Prize of the German Research Foundation (DFG).
https://www.gesundheitsindustrie-bw.de/en/article/press-release/woher-kommen-chronische-schmerzen -
urban BioEconomyLab - 07/12/2023 The city as a living laboratory for a bioeconomic, sustainable economic area
Baden-Württemberg is leading the way in the transition to a climate-neutral and sustainable economy. One of the projects undertaken is the Fraunhofer IGB’s "urban BioEconomyLab" project which aims to develop a transformation model and living laboratory to find bioeconomic solutions for the sustainable design of cities and municipal industry. What is new is that the IGB takes a systemic approach, focusing on biobased and circular value…
https://www.biooekonomie-bw.de/en/articles/news/city-living-laboratory-bioeconomic-sustainable-economic-area -
Computer-assisted genome mining - 04/12/2023 Natural product genomics opens up new avenues in the search for antibiotics
Antibiotic-resistant pathogens are increasingly endangering our health. Since most of the drugs currently in use are based on secondary metabolites produced by bacteria or fungi, the research group of Prof. Dr. Nadine Ziemert in Tübingen is developing bioinformatic tools to specifically search the genome of these organisms for previously unknown antimicrobial agents.
https://www.gesundheitsindustrie-bw.de/en/article/news/natural-product-genomics-opens-new-avenues-search-antibiotics -
Press release - 30/11/2023 Taking antibiotics back in time
University of Tübingen researchers reverse the evolution of a class of antibiotics to gain insights for the development of new drugs.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/taking-antibiotics-back-time -
Press release - 29/11/2023 Tracing the Evolution of the Cerebellum
Heidelberg scientists unveil genetic programmes controlling the development of cellular diversity in the cerebellum of humans and other mammals. The research results have now been published in the journal Nature.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/tracing-evolution-cerebellum -
Press release - 29/11/2023 EU funds research into causes and new therapies for multiple sclerosis
The progression of multiple sclerosis (MS) can usually be slowed down with medication, but a cure is currently not possible. It is now established that Epstein-Barr viruses are involved in the development of MS. However, it is not known how the pathogens trigger the disease. The European Union is now funding the international research consortium BEHIND-MS as part of its HORIZON Europe program.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/eu-foerdert-forschung-zu-ursachen-und-neuen-therapien-der-multiplen-sklerose -
Recent research shows effectiveness of biosurfactants - 28/11/2023 Combating oil spills - biosurfactants can stimulate microbial oil degradation
Oil spills from drilling platforms and tankers cause environmental pollution and a loss of biodiversity. Researchers at the University of Stuttgart, among others, are now using biosurfactants to improve the management of oil spills: their latest research shows that biosurfactants lead to better microbiological degradation of oil components in seawater compared to conventional dispersants.
https://www.biooekonomie-bw.de/en/articles/news/combating-oil-spills-biosurfactants-can-stimulate-microbial-oil-degradation -
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The AlbLavendel project - 20/11/2023 Swabian lavender cultivation: aesthetic and sustainable
Blue-violet, fragrant fields like those in Provence may soon become a common sight in the Swabian Alb. As part of the AlbLavendel project, the University of Hohenheim along with the company naturamus GmbH and the German Institutes of Textile and Fibre Research Denkendorf has started to investigate the cultivation of lavender, the production of essential oils and the use of distillation residues for producing textile fibres in the local region.
https://www.biooekonomie-bw.de/en/articles/news/swabian-lavender-cultivation-aesthetic-and-sustainable -
Press release - 15/11/2023 Nanoparticles for optimized cancer therapy
Pancreatic cancer is one of the deadliest types of cancers in humans. Chemotherapies attack not only the tumor cells but also healthy cells throughout the body. Innovative nanoparticles could be a new approach to treat cancer more precisely. The approach was developed by a research team from the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the Karlsruhe Institute of Technology.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/nanopartikel-fuer-optimierte-krebstherapie -
Augmented reality for visual orientation - 15/11/2023 Fall prevention with the help of balance-enhancing AR glasses
As we age, our eyesight deteriorates and we have increasing difficulties with orientation. This can lead to balance problems and fatal falls. A team led by Dr. Lorenz Assländer from the University of Konstanz is currently developing a prototype of augmented reality (AR) glasses that use superimposed patterns to facilitate visual orientation in space, thereby helping to improve balance control and prevent falls.
https://www.gesundheitsindustrie-bw.de/en/article/news/fall-prevention-help-balance-enhancing-ar-glasses -
Event - Sharing Knowledge about: Insect Biorefineries and AI Tools
Online, Informationsveranstaltunghttps://www.biooekonomie-bw.de/en/events/sharing-knowledge-about-insect-biorefineries-and-ai-tools -
Press release - 10/11/2023 Therapy resistance in multiple myeloma: molecular analyses of individual cancer cells reveal new mechanisms
All cancer cells - even those within the same tumor - differ from each other and change over the course of a cancer disease. Scientists at Heidelberg University Hospital, the Medical Faculty in Heidelberg and the German Cancer Research Center discovered molecular changes in multiple myeloma that help individual cancer cells to survive therapy.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/therapy-resistance-multiple-myeloma-molecular-analyses-individual-cancer-cells-reveal-new-mechanisms -
Nanoparticles as drug carriers - 09/11/2023 Inhalation of nanocarriers for antibiotics against resistant tuberculosis pathogens
Around ten million people worldwide still contract tuberculosis every year. With an estimated 1.4 million deaths a year, tuberculosis was the world’s deadliest infectious disease until COVID-19. The high mortality rate is down to the sophisticated biology of the pathogen Mycobacterium tuberculosis. A team of researchers from the KIT and the Research Centre Borstel (FZB) has developed a method that aims to outsmart the bacterium once and for all.
https://www.gesundheitsindustrie-bw.de/en/article/news/inhalation-nanocarriers-antibiotics-against-resistant-tuberculosis-pathogens -
Climate-neutral wastewater treatment plants thanks to patented real-time analytics - 08/11/2023 Using AI to reduce greenhouse gases in wastewater companies
The wastewater industry is responsible for global greenhouse gas emissions equivalent to those of global aviation. The start-up Variolytics has found a way to significantly reduce greenhouse gases in wastewater treatment plants using real-time analytics. The patented sensor technology and AI-supported process optimisation offer multiple benefits: in addition to reducing nitrous oxide, the system helps to reduce energy costs and resources.
https://www.biooekonomie-bw.de/en/articles/news/using-ai-reduce-greenhouse-gases-wastewater-companies -
Press release - 06/11/2023 Improving the efficacy of cancer immunotherapy with modified CAR-T cells
CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments are unsuccessful. A limiting factor of this very effective and safe therapy is that the cells used in the process quickly reach a state of exhaustion. Researchers at the University of Freiburg have now been able to prevent this exhaustion and thus significantly improve the effect of the therapy in a preclinical animal model.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/improving-efficacy-cancer-immunotherapy-modified-car-t-cells -
Press release - 02/11/2023 Sustainability Innovation Campus
The Sustainability Innovation Campus (ICN) initiated by the University of Freiburg and the Karlsruhe Institute of Technology (KIT), which will begin its work in January 2024, has announced a two-year funding programme for start-up projects. Scientists from the University of Freiburg, KIT and cooperating universities and research institutions are invited to submit their project outlines by 30 November 2023.
https://www.biooekonomie-bw.de/en/articles/pm/sustainability-innovation-campus -