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KyooBe Tech GmbH - 08/10/2020
For decades, conventional inactivated vaccines have been produced by killing pathogens with toxic chemicals. However, this process often changes the surface structure of the pathogens to such an extent that the immune system is only able to induce a weak response. KyooBe Tech GmbH is offering a method that uses low-energy electrons to inactivate pathogens. Vaccines produced this way are much higher quality, making them safer and more effective.
https://www.gesundheitsindustrie-bw.de/en/article/news/next-generation-vaccine-production
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Freudenberg Filtration Technologies - 01/10/2020
Filter technology can effectively remove microorganisms such as the new coronavirus from aerosols. A team of experts at Freudenberg Filtration Technologies develops and produces filtration solutions that effectively reduce the spread of viruses in cars, industrial plants and public buildings. The company’s filter technology for reducing the viral load is a reliable method for enabling people to stay in closed rooms with a high density of people.
https://www.gesundheitsindustrie-bw.de/en/article/news/coronavirus-thwarted-filters-against-aerosol-spread
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Phytopharmaceuticals - 14/09/2020
Anyone who thinks hemp is just an inconspicuous plant, whose ingredients can be used, at best, as an intoxicant, can quickly be proven wrong. Besides being used as a valuable raw material for textiles and building materials, the plant has great potential as a medicinal drug. The CANNABIS-NET network, coordinated by the University of Hohenheim, has been set up to establish the basis for producing medicinal hemp in Germany.
https://www.gesundheitsindustrie-bw.de/en/article/news/medicinal-cannabis-be-grown-germany
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Biochip systems - 02/09/2020
Dr. Peter Loskill and his team at the Fraunhofer Institute in Stuttgart and the University Hospital of Tübingen are developing what is known as an "organ-on-a-chip" (OoC). An OoC is a microfluidic system that simulates small functional units of organ tissue. OoCs can be used in different ways: in basic and pharmaceutical research as well as in clinical research and application, where they might render many animal experiments…
https://www.gesundheitsindustrie-bw.de/en/article/news/miniature-organs-great-potential
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Innovative Therapies - 20/08/2020
Labor Dr. Merk & Kollegen is reorienting its business towards viral therapeutics. With this change of strategy, the company, which has decades of expertise in virology, wants to position itself in a timely fashion in the growing new market for advanced therapy medicinal products (ATMP). In gene and virotherapies (oncolytic viruses), tumour vaccines and CAR-T cell therapies, viruses are essential as vectors, killers of tumour cells or…
https://www.gesundheitsindustrie-bw.de/en/article/news/labor-dr-merk-fully-committed-viral-therapies
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CeGat GmbH - 06/08/2020
Have I perhaps already had COVID-19 in the past? This is a question many of us have been asking. Reliable tests that would provide the answer have simply not been available until now. However, the Tübingen-based biotech company CeGaT is now offering a coronavirus antibody test to anyone who wants one, thus answering this question with the highest probability currently possible. Response to the offer has been huge in the few weeks since the test…
https://www.gesundheitsindustrie-bw.de/en/article/news/cegat-specific-coronavirus-antibody-test-all
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TGU Varimol - 24/07/2020
Using a simple molecular click process, biochemists have been able to connect ring-shaped molecules with each other and couple therapeutically active substances to these molecules. Drugs can thus be specifically delivered to diseased cells and used for imaging processes or biosensors. The Stuttgart-based start-up Varimol is using this new technology to provide its customers with tailored applications that are as simple to use as a kit.
https://www.gesundheitsindustrie-bw.de/en/article/news/click-chemistry-new-medical-procedures
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Microstructure Technology - 17/07/2020
Sensory organs are sophisticated masterpieces of nature. That is why humans have often tried to copy them. Be it cameras or microphones - there are technical objects that have always been based on natural models such as the eye or the ear. For a long time, however, no artificial sense of smell has featured in the technical repertoire. Now researchers at the Karlsruhe Institute of Technology (KIT) have developed an electronic nose. It can…
https://www.gesundheitsindustrie-bw.de/en/article/news/electronic-nose-many-applications
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Stem cell therapy for regenerating intervertebral discs - 16/07/2020
Back pain is often caused by intervertebral disc disorders. Much has already been tried and is available to help patients. Despite extensive progress, there is still no surefire recipe for success. iPSpine, an EU-funded project to which researchers from Ulm are contributing interdisciplinary engineering and biomedical expertise, aims to design a novel therapy for back pain based on intervertebral disc regeneration.
https://www.gesundheitsindustrie-bw.de/en/article/news/Ulms-simulator-has-europes-back
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Qualitative soil fertiliser - 10/07/2020
Recycled material instead of waste: wood ash is good for soil and plants - if the quality is right. The German Federal Quality Association for Food Ash ensures reliable wood ash standards with its certifications. The RAL-Dünger label for fertilisers provides the necessary certification for natural wood ashes to be used in the circular economy.
https://www.biooekonomie-bw.de/en/articles/news/how-natural-cycles-can-be-closed-wood-ash
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Review article (new edition) - 08/07/2020
Immunology is constantly changing with the emergence of new technologies and areas of application, and has branched out in many directions. Immunological approaches are central to everything – be it the development of innovative active substances and vaccinations against cancer, the search for new therapies against neurodegenerative diseases or autoimmune diseases, or combatting well-known infectious diseases or new virus epidemics.
https://www.gesundheitsindustrie-bw.de/en/article/dossier/immunology-forefront-medical-progress
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Affimed GmbH - 01/07/2020
In the fight against tumour cells, d Affimed GmbH from Heidelberg relies entirely on the weapons of the innate immune system. Affimed has developed special innate cell engagers, which are bispecific antibodies that recognise tumour cells and bring them together with natural killer cells and macrophages of the innate immune system, which then kill the tumour cells. Clinical trials using the AFM13 molecule are ongoing.
https://www.gesundheitsindustrie-bw.de/en/article/news/innate-cell-engager-fighting-against-cancer
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rezemo GmbH - 26/06/2020
In Germany alone, around three billion disposable coffee capsules made of aluminium and plastic are sold every year. This creates a gigantic waste problem, as only a small proportion of the capsules can be recycled. Fully compostable wooden coffee capsules might be a solution to this problem. The capsules have been developed by a start-up company called rezemo, which also has other biobased packaging solutions in the pipeline.
https://www.biooekonomie-bw.de/en/articles/news/coffee-capsules-wood-instead-aluminium
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Innovations in the field of endoscopy - 08/06/2020
A pill camera to examine the gastrointestinal tract that can be swallowed without major difficulty, controlled intuitively from the outside and deliver images in real time - why would any doctor or patient say no? To non-experts, it sounds more like science fiction but such a device is actually already in development: since 2019, Tübingen-based Ovesco Endoscopy AG and three partners have been working together on this in a project called nuEndo.
https://www.gesundheitsindustrie-bw.de/en/article/news/magenspiegelung-kamerapille
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Translational oncology - 26/05/2020
The fight against cancer is a pressing issue. Although technological advances in the treatment, prevention and early detection of cancer have improved over the past few decades, the number of people affected is increasing. Cancer medicine now wants to counteract this by joining forces with other players involved in the field.
https://www.gesundheitsindustrie-bw.de/en/article/news/translation-driver-cancer-medicine
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The “Rhizo-Lentil" EIP-AGRI project - 20/05/2020
NovoCarbo GmbH produces biochar from plant residues such as wood chips, nutshells and manure. Different feedstocks, and the way these materials are processed, create biochars with different properties. This makes biochar suitable for different uses, including as a soil conditioner, in biogas plants or as bedding for stables and cowsheds. The Rhizo-Linse project is currently investigating whether biochar is also suitable as inoculant carrier for…
https://www.biooekonomie-bw.de/en/articles/news/novocarbo-turns-plant-waste-into-biochar
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Trenzyme GmbH - 20/05/2020
The SARS-CoV-2 coronavirus uses a spike protein to bind to the ACE2 receptor on the cell surfaces of lung tissue. Additional cofactors are needed to allow the virus genome to penetrate human cells and multiply. Knowing these relationships can help understand the course of the infection and develop counterstrategies. To this end, the Constance-based company Trenzyme has produced a recombinant spike protein to support coronavirus research.
https://www.gesundheitsindustrie-bw.de/en/article/news/the-sars-cov-spike-protein-and-its-receptor
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Heidelberg Technology Park - 05/05/2020
How can scientists turn their know-how into marketable products and services and thereby provide society with real added value? In addition to solid financing, start-up companies need a suitable infrastructure and a dense network of partners for exchanging expertise to help them get off to a good start when it comes to setting up a business. The Heidelberg Technology Park offers company founders in the life sciences exactly these success factors.
https://www.gesundheitsindustrie-bw.de/en/article/news/start-up-support-for-life-sciences-companies
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Dossier - 28/04/2020
Biomass from forestry and agriculture along with residues from industry and households can contribute to our energy and raw material shift. Sustainable, regenerative biomass-based energy can become part of the energy mix of the future within the framework of a bioeconomy.
https://www.biooekonomie-bw.de/en/articles/news/Sustainable-bioenergy
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Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB - 24/04/2020
Every year, around 11 million people die of sepsis (blood poisoning) caused by microorganisms or microbial residues, known as pyrogens, entering the bloodstream. The smallest amounts can trigger fever. Researchers from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart have developed a pyrogen test that does not require a laboratory and is not tested on animals. It is expected to be placed on the market soon.
https://www.gesundheitsindustrie-bw.de/en/article/news/A-rapid-pyrogen-test-the-human-immune-system-as-model
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Urban agriculture - 23/04/2020
Given the challenges faced by modern agriculture, it is vital to raise people’s awareness of how to change their approach to food. The founders of the Stuttgart-based start-up company farmee GmbH see urban agriculture as the key to making this change possible. The company has developed “alphabeet”, an app designed to encourage consumers to produce their own food. After all, only those combining knowledge and practical experience can be expected…
https://www.biooekonomie-bw.de/en/articles/news/alphabeet-the-green-fingered-smartphone
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Biosensors - 09/04/2020
Sensor networks are one of the keys to achieving digitalisation of the bioeconomy. Sensor networks are on the way to becoming important analysis and control instruments for energy-efficient and sustainable material cycles. Dieter Hertweck, Professor of Business Information Systems at Reutlingen University of Applied Sciences, shows what is already possible in digital agriculture and waste recycling and what is feasible for the future.
https://www.biooekonomie-bw.de/en/articles/news/Sensors-for-the-bioeconomy
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Novel coronavirus outbreak - a status report on recent developments - 04/03/2020
Researchers around the world are working frantically on the development of a vaccine against the new coronavirus. A project by the Tübingen-based biotechnology company CureVac, funded by the Coalition for Epidemic Preparedness Innovations (CEPI), uses the company’s technology platform for mRNA-based vaccines to accelerate vaccine development, thus contributing to the future prevention of the disease.
https://www.gesundheitsindustrie-bw.de/en/article/news/Waiting-for-a-SARS-CoV-2-vaccine
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Biogas and wood as components of the energy transition - 10/02/2020
Decentralised, controllable and stable - renewable energy is an important component in the transition to a bioeconomy without fossil fuels. BIOPRO spoke to PD Dr. Andreas Lemmer from the State Institute of Agricultural Engineering and Bioenergy at the University of Hohenheim and Prof. Dr. Stefan Pelz, scientific director of the Institute for Applied Research and professorat the University of Applied Forest Sciences Rottenburg.
https://www.biooekonomie-bw.de/en/articles/news/New-perspectives-for-bioenergy
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Article - 04/02/2020
A “living pharmacy” crawls on the ocean floor off the coastline that stretches from Southern California to Mexico: biosyn Arzneimittel GmbH, a pharmaceutical company based in the city of Fellbach in southern Germany, produces a drug to treat bladder cancer, using the haemolymph, a vertebrate fluid equivalent to blood, of Megathura crenulata, commonly known as a giant keyhole limpet.
https://www.gesundheitsindustrie-bw.de/en/article/news/medicine-from-blue-blood-marine-snails
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Polysecure GmbH - 16/01/2020
Plastics are harmful to the climate and human health both during manufacture and combustion and they also clutter our planet with garbage. Recycling is therefore a key issue, but it is not efficient. Polysecure has developed a process for permanently marking individual plastics that enables them to be separated efficiently and returned to a circular economy. This would counteract the vast amount of (micro) plastics and reduce CO₂ emissions.
https://www.biooekonomie-bw.de/en/articles/recycling-of-the-future-marked-plastic-as-a-circular-product
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Producing valuable new products from waste materials - 07/01/2020
Eco-friendly and responsibly manufactured products are more in demand than ever before. Specific research is being carried out into materials and applications for a wide variety of uses. The Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB is working with Hermetia Baruth GmbH on the vision of an insect biofactory that uses waste materials to produce a wide range of products such as biosurfactants, animal feed or foils.
https://www.biooekonomie-bw.de/en/articles/news/A-vision-insect-biorefineries-as-components-of-a-sustainable-bioeconomy
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EIP-AGRI project coordination - 12/12/2019
Lentil plants, rarely cultivated in Central Europe in the twentieth century, are making a comeback. The "Rhizo-Linse"1 EIP-AGRI project aims to reintroduce old lentil varieties and make them appealing to farmers. A company called nadicom Gesellschaft für angewandte Mikrobiologie mbH is working on the development of an ecological product consisting of nodule bacteria that can improve lentil plant growth.
https://www.biooekonomie-bw.de/en/articles/news/nadicom-Rhizo-Linse-project-excellent-small-fertiliser-factories
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Biosensors - 03/12/2019
Biosensors are used in medical diagnostics and food and environmental analyses, to name just a few examples. apic.ai, a start-up based in Karlsruhe, uses honey bees as bioindicators to gain insights into the state of the ecosystem. The company also uses artificial intelligence (AI) methods for their ecotoxicological investigations.
https://www.biooekonomie-bw.de/en/articles/news/learning-from-the-bees
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CRISPR/Cas9 and genetic engineering laws - 27/11/2019
Plant geneticists from Tübingen have used genome deletion to breed a variety of tomato that is resistant to powdery mildew. The CRISPR/Cas9 technology that they used enabled them to achieve this in a relatively short period of time. They also demonstrated beyond any doubt that the new tomato variety contains no foreign DNA and is indistinguishable from naturally occurring deletion mutants.
https://www.biooekonomie-bw.de/en/articles/news/transgene-free-plant-breeding-using-genome-editing
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Dossier - 15/11/2019
The negative image of plastic persists and is not getting any better in the face of the ongoing debate about microplastics which are basically everywhere. Plastic pollutes the environment. The globe is littered with huge quantities. We have to modify the production and utilisation of macroplastics as well as fundamentally rethink the way we dispose of them. ‘Out of sight, out of mind’ mentality must become a thing of the past.
https://www.biooekonomie-bw.de/en/articles/dossiers/waste-valuable-resource-wrong-place
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Article - 08/11/2019
It is difficult to place drugs in the right place in the eye. When using droplets, only a small fraction of the drug reaches its target. Injecting drugs into the eye is also more a matter of luck than judgement. Basic researchers at the Max Planck Institute for Intelligent Systems Stuttgart have developed a nanorobot that can be loaded with active ingredients for treating eye diseases and directed through the solid tissue of the vitreous body.
https://www.gesundheitsindustrie-bw.de/en/article/news/Nanorobots-future-minimally-invasive-tools-for-eye
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Article - 22/10/2019
After successes in the treatment of advanced blood cancers, CAR T-cell immunotherapy has become a major beacon of hope in oncology. The first therapies have received regulatory approval. Despite their success, these immunotherapies can have serious side effects. The company AVA Lifescience develops antibodies with high tumour specificity to use as the basis for effective precision-guided CAR T-cell therapies that are better tolerated by patients.
https://www.gesundheitsindustrie-bw.de/en/article/news/using-car-t-cells-for-treating-cancer
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Article - 21/10/2019
Plastic plant pots are not good for the environment; strictly speaking, they should not even be disposed of in recycling bins. Alternatives such as coconut fibre pots are compostable, but not pollutant-free and not "bio" at all. The Karlsruhe-based company Fiber Engineering has developed a truly ecofriendly way to grow plants: pots made of hemp or grass, which are preserved with biological components and decompose completely within a…
https://www.biooekonomie-bw.de/en/articles/news/pflanztoepfe-aus-naturfasern-bio-ohne-wenn-und-aber
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Article - 15/10/2019
You feel unwell, but the family doctor’s practice is closed or it’s impossible to get an appointment at short notice. As part of their docdirekt project, the Baden-Württemberg Association of Statutory Health Insurance Physicians (in German: "Kassenärztliche Bundesvereinigung Baden-Württemberg (KVBW)) is now offering help for such cases. Everyone signed up to the statutory health insurance scheme will now be able to ring, contact via apps or…
https://www.gesundheitsindustrie-bw.de/en/article/news/docdirekt-smart-zum-arzt-baden-wuerttemberg
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Article - 09/10/2019
Cyber Valley Stuttgart-Tübingen is a European hotspot for artificial intelligence and home to many renowned experts and scientists. They are now joined by Gabriele Schweikert, who heads up the Computational Epigenomics research group in the Cyber Valley’s Division of Computational Biology. Schweikert is interested in exploring epigenetic mechanisms using machine learning methods.
https://www.gesundheitsindustrie-bw.de/en/article/news/epigenomik-aus-dem-cyber-valley
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Article - 30/09/2019
Autistic people have different gut microorganisms than non-autistic people. Researchers believe that a disturbed intestinal flora may play a role in developmental disorders of the brain such as autism. The emerging new field of metaproteomics could shed light onto the matter. A team led by Prof. Dr. Boris Macek from Tübingen has investigated the bacterial protein pool in the faeces of mice that display autistic behaviour.
https://www.gesundheitsindustrie-bw.de/en/article/news/do-gut-bacteria-have-something-to-do-with-autism
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Two-part interview part 2 | Prof. Dr. Ortwin Renn on the green genetic engineering debate - 26/08/2019
Many scientists are expecting revolutionary advances in research to come from new molecular biology tools such as the CRISPR/Cas gene scissors. These methods are very important for agriculture, especially plant breeding and nutrition. However, the debate on green genetic engineering 2.0 looks like it may once again be heading for ideological battles. We talked with Prof. Dr. Ortwin Renn and asked him about opportunities for better communication.
https://www.biooekonomie-bw.de/en/renn-green-genetic-engineering
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Two-part interview part 1 | Prof. Dr. Regina Birner on the green genetic engineering debate - 12/08/2019
Green genetic engineering continues to divide opinion in Germany in the same way as CRISPR/Cas and other genome editing (GE) techniques. What are the consequences for the bioeconomy, which involves key areas of biotechnology? We talked with Prof. Dr. Regina Birner, agricultural economist and head of Hohenheim University’s Department of Social and Institutional Change in Agricultural Development at the Institute of Agricultural and Social…
https://www.biooekonomie-bw.de/agricultural-economist-birner-calls-for-other-forms-of-dialogue-besides-organized-interest-groups
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Article - 01/08/2019
He swam the entire length of the River Rhine to draw attention to the contamination of rivers and oceans with plastic waste. After completing his mammoth swim, Prof. Dr. Andreas Fath decided to kill two birds with one stone and do something useful with microplastics. At the Furtwangen University of Applied Sciences campus in Villingen-Schwenningen, Fath is working on a filter system made of plastic waste that can be used to remove pollutants from…
https://www.biooekonomie-bw.de/en/articles/news/Clean-water-thanks-to-microplastics
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Article - 01/07/2019
Medicines should act as quickly as possible and ideally only at the site of disease. However, this may be difficult when the medicines are taken up via the digestive tract or the blood system. Researchers at the Max Planck Institute for Intelligent Systems in Stuttgart have now developed a biohybrid microrobot consisting of red blood cells and bacteria that can be loaded with active ingredients.
https://www.gesundheitsindustrie-bw.de/en/article/news/microswimmers-guided-drug-delivery
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