The health of nerve cells is closely linked to the auxiliary cells that surround them, the so-called glial cells. It still remains largely unknown what role glial cells play in age-related diseases.

During the growth and development of living organisms, different types of cells must come into contact with each other in order to form tissues and organs together. A small team working with Prof. Dr. Anne Classen of the Excellence Cluster CIBSS of the University of Freiburg has discovered that complex changes in form, or morphogenesis, during development are driven exclusively via the affinity of cells to each other.

Toxicologists from the University of Konstanz have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their genomes.

Whether in drinking water, food or even in the air: plastic is a global problem - and the full extent of this pollution may go beyond of what we know yet. Researchers at the Karlsruhe Institute of Technology (KIT), together with partners from the Netherlands and Australia, have reviewed conventional assumptions for the transport of plastic in rivers.

The University of Stuttgart's MobiLab Real-World Laboratory aims to make Campus Vaihingen car- and emission-free. Research areas include autonomous vehicles and inductive charging while driving. In addition, MobiLab is helping to ensure that the University of Stuttgart will also be climate-neutral in the area of mobility and transport by 2030.

What will the energy systems of the future look like? What technical foundations do we need, and how can the upcoming transformation be shaped in such a way that we involve all actors in society? Answers to such questions are to be provided by four research projects funded by the Carl Zeiss Foundation (CZS) as part of the “CZS Breakthroughs – Energy Systems of the Future” program. One of these is based at the University of Stuttgart.

Viral cancer therapy - 26/10/2022

Therapeutic viruses against tumours and metastases

Viruses can overcome cell barriers and transfer information to their host cells. They know how to make their host cell’s infrastructure work for them. This makes them excellent biotechnological tools, which a research group from the Fraunhofer IGB in Stuttgart is using to its advantage. The team is developing a therapeutic virus that not only recognises and fights tumours, but also has the potential to reach metastases.

Heidelberg University scientists are to receive three ERC Synergy Grants – three highly endowed grants of the European Research Council – for pioneering research projects by several teams working in collaboration.

Why do metastases often only appear after the original tumor has been surgically removed? Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Mannheim Medical Faculty of Heidelberg University have now published an explanation for this phenomenon. They were able to identify a messenger substance of the cancer cells that locally promotes the growth of the primary tumor.

Remaining mobile and producing without overtaxing the earth’s natural regenerative capacity: That’s the aim of the Innovation Campus “Mobility of the Future” (ICM) at the Karlsruhe Institute of Technology (KIT) and the University of Stuttgart. Here, in about 60 research projects and 40 research institutes, almost 300 scientists are working on electric motors without rare earths, novel manufacturing technologies, and self-learning software systems…

Mobil bleiben und produzieren, ohne die natürliche Regenerationsfähigkeit der Erde zu überfordern, das ist der Anspruch des InnovationsCampus Mobilität der Zukunft (ICM) am Karlsruher Institut für Technologie und der Universität Stuttgart. Fast 300 Forschende in gut 60 Forschungsprojekten und 40 -instituten arbeiten hier an Elektromotoren ohne Seltene Erden, neuartigen Fertigungstechnologien und selbstlernenden Software-Systemen für Fahrzeuge.

The Carl Zeiss Foundation is funding the "DELIVER - Data-driven Engineering of Sustainable Living Materials" project at the University of Freiburg in its "CZS Wildcard" program. In the project, scientists from the Freiburg Clusters of Excellence CIBSS and livMatS will develop sustainable wood-based materials whose properties can be precisely controlled.

The Carl Zeiss Foundation is funding the "DELIVER - Data-driven Engineering of Sustainable Living Materials" project at the University of Freiburg in its "CZS Wildcard" program. In the project, scientists from the Freiburg Clusters of Excellence CIBSS and livMatS will develop sustainable wood-based materials whose properties can be precisely controlled.

Researchers of the University of Freiburg have discovered a previously unknown function of septins in defending cells against dangerous hospital pathogens.

University of Tübingen, a leading member of Cyber Valley, Europe’s largest Artificial Intelligence (AI) research consortium and Boehringer Ingelheim launch an AI and data science fellowship program for top talents from around the world. Three to five fellowships will be awarded per year for up to three years with a target of nine to fifteen fellows in the program after five years.

Apogenix, a biopharmaceutical company developing next generation immunotherapeutics, announced today that asunercept showed statistically significant benefits for hospitalized COVID-19 patients in the ASUNCTIS trial. The open-label multi-center phase II trial investigated efficacy and safety of asunercept in 435 patients with moderate to severe COVID-19 disease.

Researchers from Freiburg and Harvard publish the three-dimensional structure of the B cell antigen receptor, shedding new light on its composition.

Dossier - 19/10/2022

More food sustainability: crucial for people and for the environment

Strawberries in winter and imported apples? You can find them in most supermarkets. This is not sustainable. Looking to the future, the way we eat needs to change in many mundane ways – and this needs to happen quickly so that future generations will also be able to enjoy a planet that is worth living on. In Baden-Württemberg, alternative nutrition concepts are being worked at pace. Many creative ideas and innovative products already exist.

Dossier - 12/10/2022

The health sector must become greener

Worldwide, the health sector is struggling with the consequences of global warming, but fatally is itself responsible for a significant proportion of greenhouse gas emissions. Studies show that hospitals and rehabilitation clinics in particular have great potential for reducing these emissions and, like the manufacturing industry, need to fundamentally revise established processes.

Across the EU, more than 300 billion items of packaging are not recycled every year because they consist of a mixture of different materials. Monomaterial packaging on the other hand is easy to recycle. However, it needs to be coated with ultra-thin barrier layers to protect delicate products just as well as compound materials do.

Across the EU, more than 300 billion items of packaging are not recycled every year because they consist of a mixture of different materials. Monomaterial packaging on the other hand is easy to recycle. However, it needs to be coated with ultra-thin barrier layers to protect delicate products just as well as compound materials do.