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Project BlindZero - 03/08/2023 Hope for patients with eye diseases: human cornea from 3D printers
Thousands of cornea transplants are performed every year. However, donors are rare and the procedure is not always without complications. Researchers at the University of Heidelberg are developing an innovative technique in the project BlindZero. It involves ‘printing’ human corneas directly onto patients’ eyes using 3D bioprinting. The reprogrammed genetically engineered cells used for this purpose are not expected to cause a rejection reaction.
https://www.gesundheitsindustrie-bw.de/en/article/news/hope-patients-eye-diseases-human-cornea-3d-printers -
Press release - 02/08/2023 Freiburg research team casts light on signal-dependent formation of mitochondria
Known as the power plant of the cell, mitochondria are essential to human metabolism. Human mitochondria consist of 1,300 different proteins and two fatty biomembranes. The vast majority of mitochondrial proteins are produced with a cleavable transport signal and have to be actively transported into the mitochondria.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/freiburger-forschungsteam-klaert-signalabhaengige-bildung-von-mitochondrien-auf -
Press release - 27/07/2023 Self-healing plastic becomes biodegradable
Konstanz chemists develop mineral plastics with numerous positive properties from sustainable basic building blocks and, together with biologists, demonstrate the material's excellent microbiological degradability.
https://www.biooekonomie-bw.de/en/articles/pm/Self-healing-plastic-becomes-biodegradable -
Press release - 27/07/2023 Materials Research: Biocatalytic Foams of Tremendous Stability and Activity
Industrial biocatalysis with enzymes is deemed to be a “game changer” in the development of a sustainable chemical industry. Enzymes can be used to synthesize an impressive range of complex molecules. Researchers of KIT have now developed a new class of materials by producing enzyme foams of tremendous stability and activity. The researchers have already filed a patent application on the process to produce enzyme foams.
https://www.biooekonomie-bw.de/en/articles/pm/materials-research-biocatalytic-foams-tremendous-stability-and-activity -
NeuroQ project - 26/07/2023 Quantum sensors for exoskeletons: can quantum physics beat paralysis?
Could people suddenly be able to move again decades after being paralysed? State-of-the-art quantum sensors integrated in exoskeletons could make this possible. Technology being developed as part of the BMBF-funded NeuroQ beacon project by researchers from organisations including the Fraunhofer IAF, the Charité in Berlin and the University of Stuttgart might achieve even more: besides facilitating movement, it could also help cure paralysis.
https://www.gesundheitsindustrie-bw.de/en/article/news/quantum-sensors-exoskeletons-can-quantum-physics-beat-paralysis -
Press release - 25/07/2023 Glyphosate impairs learning in bumblebees
What impacts do agrochemicals have on the ongoing global insect decline? Biologists at the University of Konstanz have found out that aversive learning is impaired in bumblebees exposed to glyphosate. Their study is published in the journal Science of the Total Environment.
https://www.biooekonomie-bw.de/en/articles/pm/glyphosate-impairs-learning-bumblebees -
Press release - 25/07/2023 Green Genetic Engineering: Making Mendel’s Dream Come True with Molecular Scissors
Molecular biologist Professor Holger Puchta from KIT is granted funding within a Reinhart Koselleck Project by the German Research Foundation (DFG) for work on specific restructuring of plant genomes. Puchta, a pioneer of green genetic engineering, has used molecular scissors in plants for 30 years now. His new project is aimed at using the CRISPR/Cas method to freely combine genes in crops, thus making Gregor Mendel’s dream come true.
https://www.biooekonomie-bw.de/en/articles/pm/green-genetic-engineering-making-mendels-dream-come-true-molecular-scissors -
Press release - 21/07/2023 Biosurfactants might offer an environmentally friendly solution for tackling oil spills
Can biosurfactants increase microbiological oil degradation in North Sea seawater? An international research team from the universities of Stuttgart und Tübingen, together with the China West Normal University and the University of Georgia, have been exploring this question and the results have revealed the potential for a more effective and environmentally friendly oil spill response.
https://www.biooekonomie-bw.de/en/articles/pm/biosurfactants-might-offer-environmentally-friendly-solution-tackling-oil-spills -
Press release - 20/07/2023 Animal testing under REACH: bringing numbers into the debate
So far, 4.2 million animal tests under the REACH chemical regulation: A study from Konstanz and Baltimore quantifies the number of animals that died for the hazard assessment of chemicals in the chemical industry.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/tierversuche-durch-reach-zahlen-die-debatte-bringen -
Press release - 20/07/2023 Anal Cancer Screening: New Microbiome-Associated Biomarkers Could Improve Prevention
A new study published in Nature Medicine, July 2023 has identified two novel markers for screening high-grade squamous intraepithelial lesions (HSIL), a precursor to anal cancer, from the anal microbiome of people with HIV (PWH). PWH are at a significantly higher risk of developing anal cancer. Current screening methods, such as anal cytology, have low specificity for detecting HSIL, which hinders the prevention of anal cancer.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/anal-cancer-screening-new-microbiome-associated-biomarkers-could-improve-prevention -
Tumour organoids facilitate drug discovery - 20/07/2023 Drug screening for children with cancer using patient-specific miniature tumours
Standard drugs often don’t work in children and adolescents with recurrent cancer. Researchers from the Hopp Children's Tumour Centre (KITZ) and the German Cancer Research Center (DKFZ) in Heidelberg have been looking to open up new therapy options for those affected, and have cultivated individual miniature tumours from biopsy samples to test the effectiveness of a variety of drugs within a few weeks.
https://www.gesundheitsindustrie-bw.de/en/article/news/drug-screening-children-cancer-using-patient-specific-miniature-tumours -
Press release - 18/07/2023 National Research Center for cutting-edge AI research in Tübingen celebrates inception
On Tuesday, July 18, 2023, the Tübingen AI Center held a symposium to celebrate its permanent establishment as a national AI center. Since July 1, 2022, it has received 20 million euros a year in funding from the federal government and the state.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/nationales-forschungszentrum-fuer-ki-spitzenforschung-tuebingen-feiert-seine-gruendung -
Press release - 18/07/2023 Robotically manufactured timber construction as a model for resource-efficient construction
As the world's population continues to grow, the construction industry faces the challenge of using fewer resources and switching to sustainable materials. Scientists from the Universities of Stuttgart and Freiburg are developing new interdisciplinary approaches to construction for the future.
https://www.biooekonomie-bw.de/en/articles/pm/robotically-manufactured-timber-construction-model-resource-efficient-construction -
Press release - 13/07/2023 Intelligent rubber materials
Wearable medical devices, such as soft exoskeletons that provide support for stroke patients or controlled drug delivery patches, have to be made of materials that can adapt intelligently and autonomously to the wearer's movements and to changing environmental conditions. These are the type of autonomously switchable polymer materials that have recently been developed by researchers at the University of Stuttgart and the University of…
https://www.gesundheitsindustrie-bw.de/en/article/press-release/intelligent-rubber-materials -
Event - Meet & Match - Hospital of the future
Cubex One in Mannheim, Registration deadline: Meet & Matchhttps://www.bio-pro.de/en/events/past-events/meet-und-match-hospital-future -
Press release - 12/07/2023 Danger for the world's oceans and biodiversity
Insightful study with participation from the University of Konstanz warns of human-induced impacts on the marine ecosystem.
https://www.biooekonomie-bw.de/en/articles/pm/gefahr-fuer-weltmeere-und-biodiversitaet -
Press release - 12/07/2023 Mast cells as a sensor: Enigmatic immune cells help to avoid harmful allergens
The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor that signals the animals to avoid antigens, including harmful allergens, and thereby protect themselves from health-threatening inflammatory reactions. The findings were published in the journal Nature.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/mastzellen-als-sensor-raetselhafte-immunzellen-helfen-schaedliche-allergene-zu-vermeiden -
Press release - 10/07/2023 Freiburg researchers investigate wildlife populations in ten large protected areas in Germany for the first time
7591 red deer, 3443 roe deer, 4876 wild boar, 36 wolves, 16 lynxes and 227 red foxes: These are the results of the first standardised monitoring of wildlife populations in ten large protected areas in Germany. It was carried out by scientists at the University of Freiburg led by Prof. Dr. Marco Heurich and Dr. Christian Fiderer from the Faculty of Environment and Natural Resources.
https://www.biooekonomie-bw.de/en/articles/pm/freiburg-researchers-investigate-wildlife-populations-ten-large-protected-areas-germany-first-time -
Expert interview - 05/07/2023 Every tenth of a degree matters when it comes to mitigating the consequences of global warming: sustainability measures in the laboratory
The life sciences sector consumes huge quantities of energy and resources. This needs to change and we have to think differently. But how and where can sustainability measures be sensibly applied in the laboratory without compromising the quality of research results? Dr. Kerstin Hermuth-Kleinschmidt, owner of NIUB-Nachhaltigkeitsberatung, a company from Freiburg that focuses on sustainability in life sciences, tells BIOPRO how this can be done.
https://www.gesundheitsindustrie-bw.de/en/article/news/every-tenth-degree-matters-when-it-comes-mitigating-consequences-global-warming-sustainability-measures-laboratory -
Event - - Cellulose Fibres Conference
Cologne and Online, Kongress/Symposiumhttps://www.biooekonomie-bw.de/en/events/cellulose-fibres-conference -
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Press release - 30/06/2023 Rain-Retaining Living Wall combines densification with flood protection
Climate change is causing temperatures to rise and storms to increase. In inner cities, summers are becoming a burden for people. Densification increases the amount of sealed surfaces. Green facades bring more green into cities. If textile storage structures are used, they can even actively contribute to flood protection. The German Institutes of Textile and Fiber Research (DITF) have developed a "Living Wall".
https://www.biooekonomie-bw.de/en/articles/pm/rain-retaining-living-wall-combines-densification-flood-protection -
Expert interview - 28/06/2023 Money isn't all that is needed – knowledge and networking can also help start-ups move forward
Dr. Rolf Neuhaus is one of the driving forces behind PALATINA Business Angels Rhein-Neckar e.V., a business angels association in the Rhine-Neckar metropolitan region. In an interview with BIOPRO, Neuhaus describes the association’s activities and explains where there is still catching up to be done in terms of start-up support in Baden-Württemberg.
https://www.gesundheitsindustrie-bw.de/en/article/news/money-isnt-all-needed-knowledge-and-networking-can-also-help-start-ups-move-forward -
Press release - 26/06/2023 How coral reefs can survive climate change
Astonishing results published from individual projects of the Tara Pacific expedition studying coral reefs – the entire dataset is made publicly available – coordinator is a biologist from the University of Konstanz
https://www.biooekonomie-bw.de/en/articles/pm/how-coral-reefs-can-survive-climate-change -
Press release - 23/06/2023 The molecular control centre of our protein factories
Researchers from Konstanz and Zurich have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/molecular-control-centre-our-protein-factories -
Press release - 21/06/2023 Technology Assessment: KIT Advises Bundestag for Another Five Years
The Institute for Technology Assessment and Systems Analysis of Karlsruhe Institute of Technology (KIT) has been entrusted with the continued operation of the Office of Technology Assessment at the German Bundestag (TAB) in the next five years until 2028. This unanimous decision was taken by the Parliament Committee for Education, Research, and Technology Assessment during today’s meeting (June 21, 2023).
https://www.biooekonomie-bw.de/en/articles/pm/Technology-Assessment-KIT-Advises-Bundestag-for-Another-Five-Years -
Predicting the success of cancer treatment - 20/06/2023 Focusing on gut microbiome for CAR T-cell therapy
Cancer immunotherapies use the body's own defences to fight tumour cells. An international consortium of researchers from Germany and the USA led by the DKFZ in Heidelberg has demonstrated that the effectiveness of CAR T-cell therapies greatly depends on the composition of the gut microbiome. The researchers have also developed a model for predicting the long-term response to the treatment.
https://www.gesundheitsindustrie-bw.de/en/article/news/focusing-gut-microbiome-car-t-cell-therapy -
Press release - 20/06/2023 Pangolin the inspiration for medical robot
Scientists at the Max Planck Institute for Intelligent Systems in Stuttgart have developed a magnetically controlled soft medical robot with a unique, flexible structure inspired by the body of a pangolin. The robot is freely movable despite built-in hard metal components. Thus, depending on the magnetic field, it can adapt its shape to be able to move and can emit heat when needed.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/pangolin-inspiration-medical-robot -
Press release - 20/06/2023 CureVac Doses First Patient in Phase 1 Study of Cancer Vaccine Candidate for Surgically Resected Glioblastoma
CureVac N.V. today announced that it has dosed the first patient with its investigational cancer vaccine CVGBM in a Phase 1 study. CVGBM is based on CureVac’s proprietary second-generation mRNA backbone and features a single mRNA, encoding eight epitopes derived from known tumor-associated antigens with demonstrated relevance in glioblastoma. A first data readout is expected in the second half of 2024.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-doses-first-patient-phase-1-study-cancer-vaccine-candidate-surgically-resected-glioblastoma -
Press release - 20/06/2023 Tuberculosis Therapy: Smallest Particles Will Deliver the Drug to the Lungs in Future
KIT and Research Center Borstel Present Nanoparticles with a High Antibiotic Concentration for Inhalation – Nanocarriers of Antibiotics Can Reduce Resistances and Enhance Compatibility.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/tuberculosis-therapy-smallest-particles-will-deliver-drug-lungs-future -
Press release - 16/06/2023 What determines whether breast cancer cells can form metastases?
In most cancers, it is not the growth of the primary tumor that determines the prognosis for the patient, but whether it will spread and form metastases. This process is very complex. There are often years between the development of the cancer and the aggressive growth of the metastases. Scientists from the DKFZ, the HI-STEM, the Ruhr University Bochum, Helmholtz Munich and ETH Zurich have studied and identified metastasis growth in breast cancer
https://www.gesundheitsindustrie-bw.de/en/article/press-release/what-determines-whether-breast-cancer-cells-can-form-metastases -
Innovative materials - 14/06/2023 Reinventing ‘wood’ with programmable bacteria
Conserving wood by producing furniture and other objects from wood-based materials with the help of microorganisms? That is exactly what a team of researchers from the University of Freiburg and the Leibniz Institute for New Materials (INM) in Saarbrücken is working on in the DELIVER project. The aim is to create a database of materials with a broad range of controllable properties for various applications that can be produced from wood waste.
https://www.biooekonomie-bw.de/en/articles/news/reinventing-wood-programmable-bacteria -
Press release - 13/06/2023 AutoProNano – international cooperation for in vitro and in vivo diagnostics
The AutoProNano German/French collaborative project involves developing a process for the automated production of nanoparticles for in vitro and in vivo diagnostics. The project is being launched within the smart analytics cooperation network. This international initiative has been funded by the Central Innovation Programme for SMEs (ZIM) of the German Federal Ministry for Economic Affairs and Climate Action (BMWK) since May 2020.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/autopronano-international-cooperation-vitro-and-vivo-diagnostics -
Press release - 05/06/2023 New findings about human metabolic processes
Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney. The scientists from the Institute of Genetic Epidemiology at the Medical Center - University of Freiburg measured tiny molecules, so-called metabolites, which occur in blood and urine and reflect our metabolism, in samples from more than 5,000 study participants.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-findings-about-human-metabolic-processes -
Reduced immunosuppression possible in transplantations - 05/06/2023 Modified immune cells produce donor-specific tolerance
Traditionally, transplant recipients have had to take immunosuppressive medication for life to prevent organ rejection. However, there are considerable side effects involved. Using modified immune cells (MICs), TolerogenixX GmbH from Heidelberg has now managed to generate donor-specific tolerance in recipients of living kidney transplants without suppressing the overall immune system.
https://www.gesundheitsindustrie-bw.de/en/article/news/modified-immune-cells-produce-donor-specific-tolerance -
Press release - 30/05/2023 Light conveyed by the signal transmitting molecule sucrose controls growth of plant roots
Team of Freiburg researchers shows how information about the quantity of absorbed light passes from the leaves to the roots. Plant growth is driven by light and supplied with energy through photosynthesis by green leaves. It is the same for roots that grow in the dark – they receive the products of photosynthesis, in particular sucrose, i.e. sugar, via the central transportation pathways of phloem.
https://www.biooekonomie-bw.de/en/articles/pm/licht-steuert-das-wachstum-von-pflanzenwurzeln-vermittelt-durch-das-signalmolekuel-saccharose -
Detecting drug resistance of tumour cells - 25/05/2023 AI-assisted diagnostics declares war on lung cancer
Lung cancer is one of the most common cancers and has a particularly high mortality rate. A significant challenge in treating this disease lies in the resistance of lung tumours to conventional drug therapies, rendering chemotherapy ineffective. There is hope on the horizon as a team of experts from Baden-Württemberg has joined forces to develop an innovative AI-supported test procedure that paves the way for individualised therapy approaches.
https://www.gesundheitsindustrie-bw.de/en/article/news/ai-assisted-diagnostics-declares-war-lung-cancer -
Press release - 25/05/2023 Oops, did I do that – or is there someone else in my head?
Tübingen researchers describe connection between action and feeling of authorship - finding sheds light on delusions of external control in schizophrenia
https://www.gesundheitsindustrie-bw.de/en/article/press-release/oops-did-i-do-or-there-someone-else-my-head -
Press release - 24/05/2023 Finally delicious: New proteins to revolutionize gluten-free baked goods
Daisies, peas, canola, etc.: Researchers at the University of Hohenheim want to replace gluten protein with new alternatives. Instead of ovens, 3-D printers would be possible
https://www.biooekonomie-bw.de/en/articles/pm/endlich-lecker-neue-proteine-sollen-glutenfreie-backwaren-revolutionieren -
Press release - 24/05/2023 Epigenetic profiling identifies potential COPD treatment targets
Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists have now identified potential targets for COPD treatment. The team detected early epigenetic changes in the genome of COPD fibroblasts, providing new insights into the disease pathogenesis and potential therapeutic avenues.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/epigenetic-profiling-identifies-potential-copd-treatment-targets -
Press release - 23/05/2023 B cells promote liver cancer with dangerous dual strategy
Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. In both mice and humans with NASH, they found increased numbers of activated B cells in the gastrointestinal tract.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/b-cells-promote-liver-cancer-dangerous-dual-strategy -
Press release - 22/05/2023 How plants use sugar to produce roots
Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. An international team of plant biologists has demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein.
https://www.biooekonomie-bw.de/en/articles/pm/how-plants-use-sugar-produce-roots -
Press release - 22/05/2023 Prevention of pandemics
Volkswagen Foundation to fund international research project with around 1.5 million euros. Interdisciplinary team led by the Institute for Global Health at Heidelberg University Hospital to research the transmission of pathogens from animals to humans in Thailand and Laos. Long-term goal is to develop sustainable preventive measures against future pandemics.
https://www.gesundheitsindustrie-bw.de/en/article/press-release/prevention-pandemics -
Press release - 17/05/2023 Playing hide and seek in the centromere
Centromeres, the DNA sections often found at the center of the chromosomes, display enormous interspecies diversity, despite having the same vital role during cell division across almost the entire tree of life. An international team of researchers has discovered that the variation in centromere DNA regions can be strikingly large even within a single species. The findings, now published in the journal Nature, shed light on the molecular…
https://www.gesundheitsindustrie-bw.de/en/article/press-release/playing-hide-and-seek-centromere -
3D-Thermocell project - 17/05/2023 Paper instead of plastic: sustainable packaging with a good conscience
Replacing plastic – for example in packaging – is not that easy but nevertheless urgently needed. In the 3D-Thermocell project, researchers at DHBW Karlsruhe are currently developing new plastic substitute products made of thermoformable paper as a renewable resource, which should be cheap and light and easy to dispose of along with waste paper. The characterisation and application of demonstration models will start soon.
https://www.biooekonomie-bw.de/en/articles/paper-instead-plastic-sustainable-packaging-good-conscience