Press release - 02/10/2012 Making cell division impossible: Optimized substance forces cancer cells into death Many tumor cells have a defective cellular equipment. It is only by a special trick that they manage to distribute their chromosomes correctly to their daughter cells during cell division. Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now developed a substance that thwarts this trick and forces cancer cells into death during cell division. The group has now reported their results in the journal…https://www.gesundheitsindustrie-bw.de/en/article/press-release/making-cell-division-impossible-optimized-substance-forces-cancer-cells-into-death
Press release - 02/10/2012 One- or two-way transcription depends on gene loops In certain toy racecar tracks sneaky players can flip a switch trapping their opponents vehicles in a loop of track. Cells employ a less subtle approach they change the tracks layout. In a study scientists at the European Molecular Biology Laboratory EMBL and Oxford University discovered that by forming or undoing gene loops cells manipulate the path of the transcription machinery which reads out instructions from DNA controlling whether it…https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-or-two-way-transcription-depends-on-gene-loops
Press release - 02/10/2012 Scientists find explanation for formation of connections between nerve cells Multiple synaptic contacts between nerve cells facilitate the creation of a new contact as neuroscientists from the Bernstein Center Freiburg and the Forschungszentrum Jülich report in the latest issue of the journal PLoS Computational Biology. An integral mechanism of memory foundation is the formation of additional contacts between neurons in the brain.https://www.gesundheitsindustrie-bw.de/en/article/press-release/scientists-find-explanation-for-formation-of-connections-between-nerve-cells
Article - 01/10/2012 MCAT GmbH: Highly efficient intermediates for new drugs Konstanz-based MCAT GmbH is focused on the development and production of azido-PEG glycosides, carbohydrate structures that can be used for a broad range of different applications, including the functionalisation of surfaces, the derivatisation of drugs and other compounds as well as the production of multivalent lectin ligands.https://www.gesundheitsindustrie-bw.de/en/article/news/mcat-gmbh-highly-efficient-intermediates-for-new-drugs
Dossier - 01/10/2012 Systems biology: understanding complex biological systems Systems biology studies complex interactions within biological systems on the genome proteome and organelle level. Many techniques from the fields of systems theory and associated fields can be used to gain an understanding of the behaviour and biological mechanisms of cellular systems.https://www.gesundheitsindustrie-bw.de/en/article/dossier/systems-biology-understanding-complex-biological-systems
Dossier - 01/10/2012 Systems biology: understanding complex biological systems Systems biology studies complex interactions within biological systems on the genome proteome and organelle level. Many techniques from the fields of systems theory and associated fields can be used to gain an understanding of the behaviour and biological mechanisms of cellular systems.https://www.biooekonomie-bw.de/en/articles/dossiers/systems-biology-understanding-complex-biological-systems
Press release - 28/09/2012 Safer, more effective and innovative medical devices Ranging from simple sticking plasters to the most sophisticated life-supporting machines medical devices and in vitro diagnostic medical devices are central to our health and quality of life. To ensure that these devices serve the needs and ensure the safety of European citizens the European Commission proposed two Regulations which are fit for purpose more transparent and better adapted to scientific and technological progress.https://www.gesundheitsindustrie-bw.de/en/article/press-release/safer-more-effective-and-innovative-medical-devices
Article - 24/09/2012 MTS: Shock wave technology for the therapy of diabetic foot ulcer Almost 15 percent of an estimated seven million diabetes mellitus patients in Germany suffer from diabetic foot syndrome DFS. It is associated with damage to the foot nerves and blood vessels as well as the presence of chronic wounds which in thousands of cases every year precede lower leg amputations. The Konstanz-based company MTS Medical has developed a shock wave therapy system that has the potential to considerably reduce the number of…https://www.gesundheitsindustrie-bw.de/en/article/news/mts-shock-wave-technology-for-the-therapy-of-diabetic-foot-ulcer
Article - 24/09/2012 20 millilitres of blood to diagnose Down syndrome Down syndrome, or trisomy 21, occurs when there is an extra copy of chromosome 21. LifeCodexx AG has developed PraenaTest®, an innovative diagnostic test that is able to reliably confirm or exclude trisomy 21 from a blood sample of a pregnant woman. The non-invasive test developed by the Konstanz-based biotech company has recently been placed on the market as an alternative to current invasive tests which result in up to 700 miscarriages per year…https://www.gesundheitsindustrie-bw.de/en/article/news/20-millilitres-of-blood-to-diagnose-down-syndrome
Press release - 24/09/2012 New method for identifying and measuring secreted proteins over time It is much harder to keep up with a conversation in a crowded bar than in a quiet little caf but scientists wishing to eavesdrop on cells can now do so over the laboratory equivalent of a noisy room. A new method devised by scientists at the European Molecular Biology Laboratory EMBL in collaboration with the German Cancer Research Centre DKFZ both in Heidelberg Germany provides a new approach for studying the proteins cells release to…https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-method-for-identifying-and-measuring-secreted-proteins-over-time
Article - 24/09/2012 Alzheimer’s disease researchers look into nutrition: can antioxidants protect against Alzheimer's? Citrus fruit and carrots protect against Alzheimer’s disease, a press release recently published by the University of Ulm suggests. A closer look at the language used though reveals the statement to be rather hypothetical. However, accuracy does not seem to be a concern of articles aimed at the general public, and this is exactly how expectations and hype are created. The neurologist Christine von Arnim now faces the - not inconsiderable - task…https://www.gesundheitsindustrie-bw.de/en/article/news/alzheimer-s-disease-researchers-look-into-nutrition-can-antioxidants-protect-against-alzheimer-s
Press release - 21/09/2012 Biomarkers for virus-induced cancer in the oropharynx Patients with oropharyngeal cancers have a more favorable prognosis if their tumors are caused by human papillomaviruses. Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and Heidelberg University Hospital have now identified biomarkers which enable them to differentiate cancer cases taking a favorable course from those with an unfavorable one. It may be possible to treat the two disease types…https://www.gesundheitsindustrie-bw.de/en/article/press-release/biomarkers-for-virus-induced-cancer-in-the-oropharynx
Press release - 20/09/2012 Discus throw with cancer signals The Wnt signaling protein plays an important part in embryonic development and also in the development of diseases such as cancer. It has been unknown until now just how Wnt is carried from cell to cell. Scientists of the German Cancer Research Center and Medical Faculty Mannheim of Heidelberg University have now discovered that the protein is shipped on small discus-shaped vesicles called exosomes. The researchers are now investigating whether…https://www.gesundheitsindustrie-bw.de/en/article/press-release/discus-throw-with-cancer-signals
Press release - 18/09/2012 CureVac Secures €80 Million in Series D Financing CureVac GmbH, a clinical stage biopharmaceutical company developing a new class of therapies and vaccines based on mRNA, announced on september 18 the completion of an €80 million financing round with its main investor, dievini Hopp BioTech Holding. In the next years, CureVac will use the proceeds mainly to advance the development of its two lead RNActive® cancer vaccines against prostate cancer and non-small cell lung cancer (NSCLC),…https://www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-secures-80-million-in-series-d-financing
Article - 18/09/2012 Michael Kühl: in search of the gene architects of the heart Michael Kühl is investigating the development of the heart using a broad range of different model organisms. The developmental biologist, director of the Institute of Biochemistry and Molecular Biology at the University of Ulm, also uses evolutionary and systems biology approaches for his work. Kühl’s basic research does not follow an art for art’s sake principle, but also addresses the development of new therapies for the treatment of heart…https://www.gesundheitsindustrie-bw.de/en/article/news/michael-kuehl-in-search-of-the-gene-architects-of-the-heart
Article - 17/09/2012 Alexander Wittemann: polymeric nanostructures as carriers of biomolecules Vesicles form naturally in cells and can do many things including transporting pharmaceutically active substances to tumours. However natural vesicles only have a short lifespan which can lead to the premature release of the drug enclosed within them. Alexander Wittemann a chemist at Konstanz University has successfully developed artificial biocompatible polymer vesicles with a much longer lifespan. https://www.gesundheitsindustrie-bw.de/en/article/news/alexander-wittemann-polymeric-nanostructures-as-carriers-of-biomolecules
Article - 17/09/2012 The evolution of the nervous system Inconspicuous ringed worms make it big in the field of developmental biology. Their larvae have a rudimentary nervous system with relatively simple circuits. Research involving ringed worms provides insights into the evolution of neural development as well as giving incentives for the development of practical applications.https://www.biooekonomie-bw.de/en/articles/news/the-evolution-of-the-nervous-system
Article - 17/09/2012 ZRM – Center for Regenerative Biology and Medicine The Center for Regenerative Biology and Medicine was established in 2006 as a joint facility of the University and the University Hospital of Tübingen with the primary objective of pooling and expanding research and development of regenerative therapies in the Tübingen area. The ZRM also provides advice and services to companies, research institutions and clinical users of regenerative methods. https://www.gesundheitsindustrie-bw.de/en/article/news/zrm-center-for-regenerative-biology-and-medicine
Article - 17/09/2012 Thomas Paulöhrl: spatially and temporally controlled light-induced reactions Thomas Paulöhrl, polymer chemist from the Karlsruhe Institute of Technology (KIT), was awarded the 2012 Lanxess Talent Award for his achievements in further developing light-induced click strategies that can now be used for generating various surface structures and three-dimensional frameworks. His Ph.D. thesis not only provides the basis for new ways to efficiently modify material, it also opens up new research opportunities in medical drug…https://www.biooekonomie-bw.de/en/articles/news/thomas-pauloehrl-spatially-and-temporally-controlled-light-induced-reactions
Article - 17/09/2012 Thomas Paulöhrl: spatially and temporally controlled light-induced reactions Thomas Paulöhrl, polymer chemist from the Karlsruhe Institute of Technology (KIT), was awarded the 2012 Lanxess Talent Award for his achievements in further developing light-induced click strategies that can now be used for generating various surface structures and three-dimensional frameworks. His Ph.D. thesis not only provides the basis for new ways to efficiently modify material, it also opens up new research opportunities in medical drug…https://www.gesundheitsindustrie-bw.de/en/article/news/thomas-pauloehrl-spatially-and-temporally-controlled-light-induced-reactions
Article - 17/09/2012 Biochemisty and the assembly of ammonium machines Researchers who intend to build enzymes in the laboratory need detailed knowledge about the function of the respective enzymes. Using modern biochemistry methods researchers led by Prof. Dr. Oliver Einsle from the University of Freiburg have in the last few years clarified the atomic structure of a complex bacterial protein that converts atmospheric nitrogen into a form that can be readily used by other organisms. The researchers have recently…https://www.gesundheitsindustrie-bw.de/en/article/news/biochemisty-and-the-assembly-of-ammonium-machines
Press release - 12/09/2012 Allegedly Useless Parts of the Human Genome Fulfil Regulatory Tasks The international ENCODE project aims to assemble an encyclopedia of all functional DNA elements in the human genome. The Heidelberg scientists were able to confirm in a showcase with the model organism Medaka fish that surprisingly many of the analysed elements in the non-protein-coding part of the DNA can actually regulate gene activity in a very specific way. https://www.gesundheitsindustrie-bw.de/en/article/press-release/allegedly-useless-parts-of-the-human-genome-fulfil-regulatory-tasks