The "carbonauten minus CO2 factory 1" will start production of 4,000 t of CO2-reducing plastic granules annually at favorable prices in summer 2022.

SolidCAR-T project - 15/03/2022

Modular ‘mini-factories’ for decentralised production of CAR T cells

Novel CAR T-cell therapies have proved to be promising therapeutic options for the treatment of acute leukaemias and lymphomas. Researchers from the Fraunhofer IPA in Stuttgart, the University Hospital Tübingen and the NMI in Reutlingen have joined forces in the SolidCAR-T project that aims to generate CAR T cells to combat solid tumours and produce these cells directly on site in the clinic using automated 'mini-factories'.

Elastin as artificial muscle material - 02/03/2022

Artificial muscle from proteins for diverse future applications

As far as diversity and complexity are concerned, proteins are nature's smallest marvels. Biotechnologists have already used natural proteins as a basis for the development, bespoke design and production of artificial systems. This is what the livMatS cluster of excellence at the University of Freiburg has been doing. Researchers in the cluster have successfully produced an artificial muscle from elastin that functions autonomously.

The Ministry of the Environment, Climate Protection and the Energy Sector is funding the KoalAplan project, which extends the functional scope of a wastewater treatment plant. The project, based in the Stuttgart district of Büsnau, aims at recovering raw materials from wastewater and is therefore making a positive contribution to climate neutrality, as the products obtained replace fossil raw materials and energy-intensive processes.

The Ministry for the Environment, Climate Protection and the Energy Sector is funding the new research project RoKKa which is used to prove the viability of recovering raw materials from wastewater. This adds a crucial function to the scope of a conventional sewage treatment plant. Together with the operators of the sewage treatment plants in Erbach and Neu-Ulm, the project partners demonstrate the positive contribution towards climate protection…

The RNA Printer® is CureVac’s integrated and automated manufacturing solution for RNA vaccines and therapeutics. CureVac RNA Printer GmbH to provide dedicated infrastructure to accelerate development and broaden application range of The RNA Printer®. Dr. Markus Bergmann appointed as General Manager for CureVac RNA Printer GmbH.

CureVac N.V. (Nasdaq: CVAC), a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (“mRNA”), today announced that it has dosed the first participant in a Phase 1 study of its seasonal influenza second-generation mRNA vaccine candidate, CVSQIV, developed in collaboration with GSK.

The annual highlight of the industry is the International Conference on Cellulose Fibres in Cologne (www.cellulose-fibres.eu), where the latest innovations were showcased last week: new cellulose fibre technologies for various feedstocks and a wide range of hygiene and textile products as well as alternatives to plastics and carbon fibre for lightweight constructions.

fischertechnik has set a new milestone with the Animal Friends construction kit, as the building blocks and packaging are largely made of renewable resources and the models depict playful animals in new colours. The company is thereby taking another major step towards sustainability. The bio-based building set recently won the Toy Award, one of the most prestigious awards in the industry.

Making important raw materials for fine chemicals out of carbon dioxide really works. As part of the Max Planck collaborative project eBioCO2n, a team of researchers from Fraunhofer IGB have successfully performed a first ever fixation of CO2 via a multi-enzyme enzyme reaction driven by electricity yielding a prospective intermediate for the chemical industry. The process for electro-biocatalytic CO2 fixation was recently published and is…

Chitin is the main component of insect carapaces and ensures that they are both stable and flexible. The Chitinfluid research project, funded by the Carl Zeiss Foundation, focuses on the use of chitin in construction and aims to process chitin and its derivatives into sustainable materials. In a hybrid symposium under the auspices of Prof. Sabine Laschat from the University of Stuttgart, the project team discussed the current state of research…

Dossier - 16/12/2021

Advanced therapy medicinal products: gene and cell therapies

Novel gene and cell therapies for treating incurable and hereditary diseases have raised high expectations. However, success has so far been limited to the long-established bone marrow transplants involving the administration of haematopoietic stem cells used to treat blood cancer. CAR T-cell therapies have recently emerged as a major new hope in cancer treatment.

For the second time, the nova Institute for Ecology and Innovation is honouring outstanding scientific research that provides sustainable solutions for the cellulose fibre value chain as part of the "International Conference on Cellulose Fibres 2022". The DITF Denkendorf is one of the six nominees.

Plant residues - 14/12/2021

Straw pulp: agricultural residues become sanitary paper products

Straw cannot yet be spun into gold, but in Mannheim, Germany, it is being turned into something else of great value: Essity is the first and only company in Europe to produce toilet paper and kitchen rolls from wheat straw in a new pulp mill. From next year, these sustainable sanitary paper products will be found on supermarket shelves.

Today, the EU Parliament adopted the EU Regulation on Health Technology Assessment (HTA), which includes not only new medicines (including gene and cell therapies), but also medical devices.

Parkinson's disease is characterised by a slow, progressive loss of nerve cells in certain brain areas. The disease is still incurable and the exact causes are unclear. The dopamine deficiency in the brain can only be controlled to some extent in the initial phase of the disease. Basic research is being conducted in an attempt to unravel the mystery of Parkinson's disease.

In reforestation projects, the seedlings must be protected. So-called growth covers prevent game from feeding on the young plants and help to ensure that they are not prevented from growing by other plants. Previously used sheaths made of plastic and metal are often not removed in time and pollute the environment. The DITF have developed a biodegradable yarn for growth covers from renewable raw materials.

At the University Hospital Tübingen, clinical evaluation of an in-house developed vaccine (CoVac-1) against SARS-CoV-2 was started in November 2020 under the direction of Prof. Dr. Juliane Walz in the CCU Translational Immunology of the Medical Clinic (Medical Director Prof. Dr. Helmut Salih). Now the results of the Phase I study are available and demonstrate a potent activation of the T-cell response against the coronavirus.

The Cluster of Excellence IntCDC of the University of Stuttgart presents the "Maison Fibre" at the International Architecture Exhibition Venice. The full-scale inhabitable installation is made from robotically produced, fibrous building elements.

Dossier - 17/11/2021

Biorefinery: new paths to build our tomorrow

Sustainability is in vogue. And it’s not a question of wanting to be sustainable, but having to be: as the latest report from the Intergovernmental Panel on Climate Change shows, protecting the climate and the environment calls for swift action. Biorefineries that use renewable raw materials and recycle industrial raw materials are playing an important role in the bioeconomy concepts of many countries - including the state of Baden-Württemberg.

Plastic products can be found everywhere in daily life, soft plastic in particular often being used for packaging or children's toys. These often contain so-called plasticizers which ensure that the material remains flexible. Because plasticizers are not bonded permanently to the plastic, they can escape from the material, meaning they can be absorbed by humans.

Upcycling of lignin - 26/10/2021

Bioeconomic model project: vanillin from process industry residues

Extracting vanillin from lignin dissolved in black liquor and developing it into a process that can be scaled up for industry is a bioeconomic approach that researchers at Biberach University of Applied Sciences and Ulm University are pursuing in a five-year project.

Prof. Dr. Harald Gießen from the Institute of Physics (4) as well as Prof. Dr. Alois Herkommer and Dr. Simon Thiele from the Institute of Applied Optics at the University of Stuttgart received the Gips Schüle Research Award 2021 on October 19, 2021. The researchers were awarded the prize, which is valued at EUR 50,000.