Heidelberg Technology Park - 05/05/2020

Start-up support for life sciences companies

How can scientists turn their know-how into marketable products and services and thereby provide society with real added value? In addition to solid financing, start-up companies need a suitable infrastructure and a dense network of partners for exchanging expertise to help them get off to a good start when it comes to setting up a business. The Heidelberg Technology Park offers company founders in the life sciences exactly these success factors.

Dossier - 28/04/2020

Sustainable bioenergy

Biomass from forestry and agriculture along with residues from industry and households can contribute to our energy and raw material shift. Sustainable, regenerative biomass-based energy can become part of the energy mix of the future within the framework of a bioeconomy.

Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB - 24/04/2020

A rapid pyrogen test: the human immune system as model

Every year, around 11 million people die of sepsis (blood poisoning) caused by microorganisms or microbial residues, known as pyrogens, entering the bloodstream. The smallest amounts can trigger fever. Researchers from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart have developed a pyrogen test that does not require a laboratory and is not tested on animals. It is expected to be placed on the market soon.

Urban agriculture - 23/04/2020

alphabeet – the green-fingered smartphone

Given the challenges faced by modern agriculture, it is vital to raise people’s awareness of how to change their approach to food. The founders of the Stuttgart-based start-up company farmee GmbH see urban agriculture as the key to making this change possible. The company has developed “alphabeet”, an app designed to encourage consumers to produce their own food. After all, only those combining knowledge and practical experience can be expected…

Prime Vector Technologies GmbH (PVT), a start-up company based in Tübingen in southern Germany, uses a modular brick system to develop vaccines against cancer and infectious diseases. The PVT team is currently working flat out to develop a COVID-19 vaccine.

Biosensors - 09/04/2020

Sensors for the bioeconomy

Sensor networks are one of the keys to achieving digitalisation of the bioeconomy. Sensor networks are on the way to becoming important analysis and control instruments for energy-efficient and sustainable material cycles. Dieter Hertweck, Professor of Business Information Systems at Reutlingen University of Applied Sciences, shows what is already possible in digital agriculture and waste recycling and what is feasible for the future.

Bioinspired technologies - 03/04/2020

Diagnostics with molecular scissors – is this also possible for on-site COVID-19 tests?

The CRISPR-Cas gene-editing technology is one of the most important developments in molecular biology in recent years. It utilises molecular scissors with which nucleic acids can be cut and edited almost arbitrarily. Researchers in Freiburg, Germany have now successfully used the technology for diagnostic purposes. They are currently working intensively on expanding the system to enable it to detect genome sequences of the novel SARS-CoV-2 virus.

Multiple sclerosis - 12/03/2020

Direct application of biopharmaceuticals through the nose into the brain

There is currently no cure for multiple sclerosis, the most common neurological autoimmune disease in humans. Biopharmaceuticals that can delay the course of the disease or diminish its effects are often prevented from being fully effective by the blood-brain barrier. A European consortium led by the Fraunhofer IGB, Stuttgart is developing a new technology that can transport an innovative active ingredient directly to the central nervous system.

Novel coronavirus outbreak - a status report on recent developments - 04/03/2020

Waiting for a SARS-CoV-2 vaccine

Researchers around the world are working frantically on the development of a vaccine against the new coronavirus. A project by the Tübingen-based biotechnology company CureVac, funded by the Coalition for Epidemic Preparedness Innovations (CEPI), uses the company’s technology platform for mRNA-based vaccines to accelerate vaccine development, thus contributing to the future prevention of the disease.

The “Rhizo-Lentil" EIP-AGRI project - 03/03/2020

University of Hohenheim wants to improve the conditions for lentil cultivation

Lentils were once considered poor man’s food, but in Germany demand for them has never been greater. And to satisfy this growing demand, more lentils need to be cultivated. This is why the University of Hohenheim is involved in the EIP-AGRI "Rhizo-Linse" project. The aim of the project is to find rhizobia strains that go well with lentil plants to increase yield and improve quality.

Biogas and wood as components of the energy transition - 10/02/2020

New perspectives for bioenergy

Decentralised, controllable and stable - renewable energy is an important component in the transition to a bioeconomy without fossil fuels. BIOPRO spoke to PD Dr. Andreas Lemmer from the State Institute of Agricultural Engineering and Bioenergy at the University of Hohenheim and Prof. Dr. Stefan Pelz, scientific director of the Institute for Applied Research and professorat the University of Applied Forest Sciences Rottenburg.

Article - 04/02/2020

Medicine from the blue blood of marine snails

A “living pharmacy” crawls on the ocean floor off the coastline that stretches from Southern California to Mexico: biosyn Arzneimittel GmbH, a pharmaceutical company based in the city of Fellbach in southern Germany, produces a drug to treat bladder cancer, using the haemolymph, a vertebrate fluid equivalent to blood, of Megathura crenulata, commonly known as a giant keyhole limpet.

Article - 20/01/2020

Brain tumour patients could benefit from heavy ion therapy

Glioblastoma is a malignant brain tumour. It does not respond anywhere near as well to conventional forms of therapy than other tumours because it contains particularly resistant cancer cells. Scientists at the Heidelberg Ion Beam Therapy Center (HIT) at Heidelberg University Hospital and the German Cancer Research Center have shown that heavy ion therapy is effective against these cells.

Polysecure GmbH - 16/01/2020

Recycling of the future – marked plastic as a circular product

Plastics are harmful to the climate and human health both during manufacture and combustion and they also clutter our planet with garbage. Recycling is therefore a key issue, but it is not efficient. Polysecure has developed a process for permanently marking individual plastics that enables them to be separated efficiently and returned to a circular economy. This would counteract the vast amount of (micro) plastics and reduce CO₂ emissions.

Producing valuable new products from waste materials - 07/01/2020

A vision: insect biorefineries as components of a sustainable bioeconomy

Eco-friendly and responsibly manufactured products are more in demand than ever before. Specific research is being carried out into materials and applications for a wide variety of uses. The Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB is working with Hermetia Baruth GmbH on the vision of an insect biofactory that uses waste materials to produce a wide range of products such as biosurfactants, animal feed or foils.

EIP-AGRI project coordination - 12/12/2019

nadicom: “Rhizo-Linse” project – excellent small fertiliser factories

Lentil plants, rarely cultivated in Central Europe in the twentieth century, are making a comeback. The "Rhizo-Linse"1 EIP-AGRI project aims to reintroduce old lentil varieties and make them appealing to farmers. A company called nadicom Gesellschaft für angewandte Mikrobiologie mbH is working on the development of an ecological product consisting of nodule bacteria that can improve lentil plant growth.

Dossier - 06/12/2019

Microbiome: human health is closely connected with our microbial communities

People have 1.3 times more microorganisms than body cells. This microbial community influences how we digest our food, how active our immune system is, as well as whether we tend to be more anxious or curious. A number of diseases have also been shown to be associated with a disturbed microbiome. Researchers still have a long way to go before the knowledge acquired can be used for developing therapies.

Biosensors - 03/12/2019

Learning from honey bees

Biosensors are used in medical diagnostics and food and environmental analyses, to name just a few examples. apic.ai, a start-up based in Karlsruhe, uses honey bees as bioindicators to gain insights into the state of the ecosystem. The company also uses artificial intelligence (AI) methods for their ecotoxicological investigations.

CRISPR/Cas9 and genetic engineering laws - 27/11/2019

Transgene-free plant breeding using genome editing

Plant geneticists from Tübingen have used genome deletion to breed a variety of tomato that is resistant to powdery mildew. The CRISPR/Cas9 technology that they used enabled them to achieve this in a relatively short period of time. They also demonstrated beyond any doubt that the new tomato variety contains no foreign DNA and is indistinguishable from naturally occurring deletion mutants.

Article - 18/11/2019

Researchers successfully rejuvenate the immune system in animal models

It is well known that stem cells age. Even the human immune system loses its power with age. Since all immune cells are derived from blood-forming stem cells, it is quite natural to associate the weakening of the immune system (immune senescence) with the ageing of blood-forming stem cells. Stem cell researchers and immunologists from the University of Ulm have now demonstrated the important role that blood-forming cells play in the ageing of the…

Dossier - 15/11/2019

Microplastics waste is a valuable resource – it is just in the wrong place

The negative image of plastic persists and is not getting any better in the face of the ongoing debate about microplastics which are basically everywhere. Plastic pollutes the environment. The globe is littered with huge quantities. We have to modify the production and utilisation of macroplastics as well as fundamentally rethink the way we dispose of them. ‘Out of sight, out of mind’ mentality must become a thing of the past.

Article - 08/11/2019

Nanorobots as future minimally invasive tools for the eye

It is difficult to place drugs in the right place in the eye. When using droplets, only a small fraction of the drug reaches its target. Injecting drugs into the eye is also more a matter of luck than judgement. Basic researchers at the Max Planck Institute for Intelligent Systems Stuttgart have developed a nanorobot that can be loaded with active ingredients for treating eye diseases and directed through the solid tissue of the vitreous body.