Bioeconomy

Article - 30/11/2015

Bacterial MccA is better than other enzymes when it comes to reducing sulphites

Dr. Bianca Hermann from the University of Freiburg specialises in multi-haem enzymes, and investigates the enzymes’ structure and reaction mechanisms. She has clarified the enzymes’ crystal structure and reaction mechanisms and found out why the bacterial MccA enzyme complex can reduce sulphur-containing substances such as sulphites up to a hundred times faster than other enzymes.

Article - 05/07/2010

ASA Spezialenzyme GmbH – more biogas thanks to optimised enzymes

ASA Spezialenzyme GmbH offers solutions for a broad range of applications – enzymes for quicker biogas production, enzymes for rust removal or enzymes for the production of new biopolymers in cars. The company has been coming up with innovative ideas for the biotechnology market ever since it was established in 1991.

Article - 30/03/2015

Nitrogenases: magicians that convert carbon monoxide into hydrocarbons

Rhizobia soil bacteria live in symbiosis with legumes and are masters of ammonia synthesis thanks to an enzyme called nitrogenase. Prof. Dr. Oliver Einsle from the Institute of Biochemistry at the University of Freiburg is studying how the enzyme accomplishes this energy-intensive process and why it sometimes also converts other compounds with an amazing result. Einsle elucidated a mechanism by which the enzyme converts toxic carbon monoxide into…

Process engineering - 17/05/2017

Enzymes help save costs and protect the environment

The Biopolymers/Biomaterials cluster was one of five clusters that won the BioIndustry 2021 competition in 2007 and that received funding from the German Federal Ministry of Education and Research (BMBF). The cluster’s ”Biotechnological process development for novel membranes based on collagen” research project was funded by the BMBF from 1st February 2013 to 31st January 2016. The project involved four companies and one university and aimed at…

Article - 30/01/2019

candidum – computer-assisted enzyme design

Industry has been using enzymes for over a hundred years. While it initially had to content itself with natural enzymes, it is now increasingly possible to design tailor-made biocatalysts with specific properties. The start-up company candidum GmbH from Stuttgart promises to achieve this faster than ever before - mostly thanks to accelerated virtual screening.

Making important raw materials for fine chemicals out of carbon dioxide really works. As part of the Max Planck collaborative project eBioCO2n, a team of researchers from Fraunhofer IGB have successfully performed a first ever fixation of CO2 via a multi-enzyme enzyme reaction driven by electricity yielding a prospective intermediate for the chemical industry. The process for electro-biocatalytic CO2 fixation was recently published and is…

Article - 11/11/2015

A metal enzyme that can cleave benzene rings

Aromatic rings are extremely stable and very difficult to break apart. Prof. Dr. Matthias Boll from the University of Freiburg’s Faculty of Biology and his team work with Geobacter metallireducens, a bacterium that can completely degrade aromatic compounds under strictly anaerobic conditions. While the biological degradation of aromatic hydrocarbons is of global relevance, the chemical resulting from the reduction of benzene rings could also be…

Article - 13/10/2014

Crude mushroom solution to degrade micropollutants and increase the performance of biofuel cells

Sabine Sané, a doctoral student in the Department of Microsystems Engineering (IMTEK) at the University of Freiburg, has developed a concept that shows how micropollutants can be degraded in wastewater and how the latter can serve as a valuable source of raw materials. She is one of four researchers who have been awarded the 2014 Huber Technology Prize “Future Water” with a purse of 10,000 euros. Her concept is based on an enzyme that is secreted…

Article - 01/04/2013

Insights into the secrets of DyP peroxidases

AauDyP a DyP peroxidase enzyme found in tree ear mushrooms and other members of the haem peroxidase family are the major field of research of Prof. Dr. Dietmar Plattners research group at the Institute of Organic Chemistry at the University of Freiburg. Plattners co-workers Dr. Klaus Piontek and Eric Strittmatter along with colleagues from the International Institute Zittau have clarified the atomic structure of AauDyp using crystallographic…

Article - 05/01/2010

Biocatalysis – a perfect mission for Bernhard Hauer

Even though human beings are great inventors, nature itself frequently comes up with the best solutions. One good example is enzymes: in contrast to the processes used in the technical-chemical production of basic industrial substances, enzymatic biocatalysis saves energy, raw materials and reduces side and waste products. Prof. Dr. Bernhard Hauer, the new director of the Institute of Technical Biochemistry (ITB) at the University of Stuttgart is…

Article - 23/07/2012

Inhospitable niches are a rich source of extremozymes

At first sight nothing much seems to grow in either the Namib desert or the Antarctic. However a closer inspection of the ground a few centimetres below the surface reveals an enormous diversity of organisms. Industry is well aware of this rich source of microorganisms that have something to offer on the molecular level as well as for use in technical applications. So-called extremozymes have long been popular ingredients in cosmetics detergents…

Dossier - 09/12/2013

Industrial biotechnology – biological resources for industrial processes

Industrial or white biotechnology uses microorganisms and enzymes to produce goods for industry, including chemicals, plastics, food, agricultural and pharmaceutical products and energy carriers. Renewable raw materials and increasingly also waste from agriculture and forestry are used for the manufacture of industrial goods.

Article - 29/07/2013

‘Go back to start’ in the field of meiosis

Researchers have long thought they knew exactly how meiosis, meiosis regulators and the complex that forms between homologous chromosomes during meiosis work. The research group headed by Dr. Andrea Pichler from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has now discovered a new mechanism that plays an important role in meiosis. The study carried out by Pichler and her colleague Dr. Helene Klug has shown why it is…

Article - 30/03/2009

Bacteria can determine the flavour of wine

What is the connection between biotechnology and wine production? The answer is that there are more than 150 yeasts currently on the market that are used to influence the fermentation and hence the quality of wine. Enzyme preparations optimise the different steps in wine production. Dr. Jürgen Sigler from the State Institute of Viticulture and Oenology WBI is working on the development of biological methods to improve the flavour and taste of…

Article - 18/02/2011

How microorganisms gather together a metabolic pathway

Many microorganisms are found in remote places in conditions of extreme heat, extreme cold or in areas with high salt concentrations. The majority of microorganisms feed on low-molecular carbon compounds, which gives rise to the question as to how they manage to turn these compounds into cell building blocks. In a recent publication in the renowned journal Science, Dr. Ivan Berg and his group of researchers at the University of Freiburg report on…

Dossier - 09/08/2010

Molecular design made to measure and the requirements

Biomolecules such as peptides and nucleic acids can nowadays be synthesised relatively quickly and inexpensively. In addition, great progress has been made in the development of methods enabling the directed mutagenesis in microorganisms. These two developments have boosted the design of new, and the reorganisation of known, molecules. Moreover, these help in the utilisation of certain molecule functions in research and in the industrial…

Article - 13/02/2012

Emcid Biotech GmbH: mosses as gold mines

Mosses are a great source of molecules that offer protection against microorganisms dehydration and other stress factors but it is a potential that has yet to be fully exploited. Freiburg-based Emcid Biotech GmbH is developing a platform for the identification development and industrial production of natural substances and enzymes of lower plants in particular those of mosses.

Article - 23/07/2012

The heat is on – unknown biochemistry in extreme situations

Most of what is easily accessible has in principle already been discovered said Dr. Ivan Berg from the University of Freiburg explaining why he is investigating the metabolic pathways in extremophilic microorganisms. The researcher and his team are interested in the biochemistry of organisms living in hot volcanic springs and the Dead Sea. Examples of this are two metabolic pathways which the researchers from Freiburg discovered in organisms…

Article - 22/10/2009

On the track of fascinating diatoms

Diatoms make a considerable contribution to the production of oxygen and biomass in the worlds oceans and aquatic ecosystems. However up until now little is known about the molecular biology and chemistry of these eukaryotic algae. Prof. Peter Kroth and his team at the University of Constance are hoping to shed more light on these algae. The team has recently been involved in the deciphering of the Phaeodactylum tricornutum genome research that…

Article - 18/03/2013

Insights into life in the eternal ice

Life can also be found in Arctic and Antarctic ice. Anique Stecher a biologist at Konstanz University is investigating the biodiversity in these areas using samples collected on board a research vessel and then analysing the data using special phylogenetic software. This provides her with a comprehensive inventory of Arctic and Antarctic organisms and with insights into their relationships with each other. The researchers findings make an…

Article - 20/12/2010

Determination of the risk potential of particulate matter from wood combustion

Polycyclic aromatic hydrocarbons found in particulate matter in our environment are currently being studied by a network of institutes and research institutions, both in Germany and around the world. The impact of polycyclic aromatic hydrocarbons and other toxic components of particulate matter on human and animal health is not yet known in detail. However, their impact on the development of lung diseases such as asthma and other chronic…

Press release - 05/08/2013

greenovation Biotech GmbH – production of therapeutic proteins in moss

Plants can be genetically modified in a way that enables them to produce pharmaceutically active proteins for various indications. The small moss Physcomitrella patens is able to produce more complex molecules than bacteria. Moreover, moss is less expensive to grow and less susceptible to pathogenic contaminants than Chinese hamster ovary (CHO) cells. greenovation Biotech GmbH, which has its headquarters in Heilbronn and a branch in Freiburg,…

Dossier - 20/03/2017

Lignin – a natural resource with huge potential

Petroleum is the lifeblood of the chemical industry. It is the raw material for basic chemicals and is used to produce a tremendous wealth of products. Growing demand and dwindling resources mean that the chemical industry is increasingly focusing on renewable resources. Lignin is a wood component that is proving to be a particularly promising resource. It is currently almost exclusively used for generating energy, although it could also be used…

Article - 31/05/2013

Research in Biberach – does the bioeconomy have a purple future?

Rhodospirillum rubrum bacteria have long attracted the interest of biotechnologists due to their ability to produce large quantities of pigments. Microbiologist Hartmut Grammel from Biberach University of Applied Sciences and scientists from the Magdeburg-based Max Planck Institute for Dynamics of Complex Technical Systems are studying the bacterias suitability for the fixation of CO2 with the distant objective of producing organic materials with…

Article - 11/06/2010

Recycling of bacterial cell wall constituents

Bacterial cells are focused on growth and proliferation. These processes are initiated by cellular enzymes that break up the cell wall material murein introduce new material and degrade material that is no longer needed. And all this in large amounts about 50 per cent of murein are degraded and newly formed turnover per cell generation. Dr. Christoph Mayer and his team from the University of Constance have shown that the cells carry out effective…